ASD

GO:0031398 positive regulation of protein ubiquitination (113)

GeneInput weightStandardRank
PSMA1--58
PSMD14--104
PSMA4--166
FBXW7--198
PSMB3--234
PSMA5--284
PSMD8--371
PSMA3--460
CUL1--478
PSMB1--501
PSMC6--679
PSMD6--688
UBE2N--734
PSMB7--745
PSME4--787
PSMC2--815
PSMD11--967
PSMB4--1091
PSMD1--1168
PSMA7--1174
SMAD7--1192
PSMC4--1269
FKBP1A--1284
PSMC1--1296
PTEN1.011389
PSMA6--1510
PSMD12--1573
PSMB6--1607
RCHY1--1615
PSMD2--1706
BTRC--1884
PSMC5--1897
PSMD3--2008
UBE2S--2043
PSMD4--2087
CDC14B--2176
PSMC3--2240
PSMD10--2412
PSMD7--2481
FGFR3--12640
PSMA2--2699
PAXIP1--2915
FZR1--2920
PSMD13--3051
SMURF1--3060
PELI1--3259
BMI1--3300
TSPYL5--3354
ANGPT1--4182
STUB1--4250
AXIN1--14419
ANAPC2--5008
SKP1--5249
PRICKLE1--15552
DNAJB2--6026
NDFIP1--6744
UBC--6756
PIN1--7940
UBE2E1--7950
LRRK2--18802
CDC27--9665
HSPBP1--9785
MAPK15--9863
PSMA8--10087
NDFIP2--10157
PSMB2--11986
PSMB11--12480
WFS10.25112793
NHLRC1--113198
MALT1--13522
PSMD9--13911
PSME2--14327
CDC23--14728
ANAPC11--14928
HSPA5--19143
UBB--19448
PSMD5--19823
FBXO4--20319
RIPK2--20830
TRIB3--20863
PSME1--21072
ANAPC10--21179
PSMB9--21373
PSMB10--21853
TICAM1--21880
PSMB8--22146
PSME3--22162
RASSF1--22228
CDC26--22265
BCL10--122368
PSMF1--22424
TBC1D7--23126
FBXO22--23669
COMMD1--24027
SPHK1--24069
RPS27A--24381
UBA52--24384
ANAPC4--24419
BRCA1--124573
ANAPC7--24632
UBE2D1--24988
CDC16--24989
CDK1--25053
CCNB1--25174
ANAPC1--25203
PSMB5--25250
ANAPC5--25367
CLU--25437
FBXO5--25488
CDC20--25608
DNAJA3--25610
UBE2C--25614
PLK1--25783

Network

GO:0031398

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3

Troyanskaya Laboratory - Princeton University