ASD

GO:0032856 activation of Ras GTPase activity (21)

GeneInput weightStandardRank
RASGRF1--335
SIPA1L1--716
TSC10.251790
NDEL10.2511074
RALGAPA1--1420
PTK2B--3063
RALGAPA2--4803
RHOG--6279
SYDE2--7604
FOXJ1--7628
CXCL13--8148
SYDE1--9690
TAX1BP3--15553
EPHA2--119467
DOCK7--19597
ARHGEF16--21200
CCL21--21829
RALGAPB--22093
CCR7--22367
GPR65--22555
SCRIB--23676

Network

GO:0032856

Network
Enrichment
NameDescriptionExternal IDs
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1 Entrez:5923  HGNC: 9875  Ensembl: ENSG00000058335 
SIPA1L1signal-induced proliferation-associated 1 like 1 Entrez:26037  HGNC: 20284  HPRD: 11559  Ensembl: ENSG00000197555 
TSC1tuberous sclerosis 1 Entrez:7248  Ensembl: ENSG00000165699  HGNC: 12362  HPRD: 05594 
NDEL1nudE neurodevelopment protein 1-like 1 Entrez:81565  HGNC: 17620  HPRD: 06340  Ensembl: ENSG00000166579 
RALGAPA1Ral GTPase activating protein, alpha subunit 1 (catalytic) Entrez:253959  HGNC: 17770  HPRD: 12324  Ensembl: ENSG00000174373 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
SIPA1L1signal-induced proliferation-associated 1 like 1
TSC1tuberous sclerosis 1
NDEL1nudE neurodevelopment protein 1-like 1
RALGAPA1Ral GTPase activating protein, alpha subunit 1 (catalytic)
Query geneGeneGene descriptionEdge score
RASGRF1RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
SIPA1L1SIPA1L1signal-induced proliferation-associated 1 like 1
TSC1TSC1tuberous sclerosis 1
NDEL1NDEL1nudE neurodevelopment protein 1-like 1
RALGAPA1RALGAPA1Ral GTPase activating protein, alpha subunit 1 (catalytic)

Troyanskaya Laboratory - Princeton University