GO:0070374 positive regulation of ERK1 and ERK2 cascade (56)

GeneInput weightStandardRank
FBXW7--198
FGFR2--1237
SPRY2--1454
MIF0.2511552
DCC--1687
ESR10.2511791
ADRA1A--1858
BMPER--3497
PDGFA--3731
DRD20.2513749
NOX4--3804
EDNRA--13857
FGF23--13888
ANGPT1--4182
FGF20--4263
FGF10--14532
IL1A--4651
FGF4--4938
HRAS0.2515086
GCG--5190
TNFSF11--15271
TNFRSF11A--15293
TEK--5322
FGF18--6382
BMP4--16499
FGF21--7209
GPR55--8693
GPER1--9912
ARRB2--10647
IL1B--110818
BRAF--111149
IL26--11645
ARHGAP8--11916
VEGFB--11980
FGF19--12130
IL6--112695
FGF2--13150
SEMA7A--13700
CCL19--14578
TNF0.25115243
ARRB1--19906
F2RL1--19969
F2R--20036
TIRAP--20658
CD44--20701
RIPK2--20830
PDGFB--21071
NOD2--121514
CCL21--21829
S100A7--22068
CCR7--22367
ST5--22969
PDGFRB--23242
NOD1--23388
CD74--24030
GAS6--25481

Network

GO:0070374

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
SPRY2sprouty homolog 2 (Drosophila) Entrez:10253  Ensembl: ENSG00000136158  HPRD: 03916  HGNC: 11270 
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor) Entrez:4282  HGNC: 7097  HPRD: 01091 
DCCdeleted in colorectal carcinoma Entrez:1630  HGNC: 2701  HPRD: 00391 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR2fibroblast growth factor receptor 2
SPRY2sprouty homolog 2 (Drosophila)
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)
DCCdeleted in colorectal carcinoma
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR2FGFR2fibroblast growth factor receptor 2
SPRY2SPRY2sprouty homolog 2 (Drosophila)
MIFMIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)
DCCDCCdeleted in colorectal carcinoma