ASD

GO:0022408 negative regulation of cell-cell adhesion (16)

GeneInput weightStandardRank
PIK3R10.251150
MAP2K10.251907
LEF1--1499
EPB41L5--2335
SERPINE2--3708
TNR--3868
WNT1--4383
ZNF703--5031
NF2--15991
ADIPOQ0.2516032
B4GALNT2--7665
PODXL--13125
FXYD5--15475
TGFB10.25120135
GTPBP4--23572
CDH1--123589

Network

GO:0022408

Network
Enrichment
NameDescriptionExternal IDs
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HGNC: 6840  HPRD: 01469 
LEF1lymphoid enhancer-binding factor 1 Entrez:51176  HGNC: 6551  Ensembl: ENSG00000138795  HPRD: 01075 
EPB41L5erythrocyte membrane protein band 4.1 like 5 Entrez:57669  Ensembl: ENSG00000115109  HGNC: 19819  HPRD: 13273 
SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 Entrez:5270  Ensembl: ENSG00000135919  HGNC: 8951  HPRD: 01510 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
MAP2K1mitogen-activated protein kinase kinase 1
LEF1lymphoid enhancer-binding factor 1
EPB41L5erythrocyte membrane protein band 4.1 like 5
SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
Query geneGeneGene descriptionEdge score
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1
LEF1LEF1lymphoid enhancer-binding factor 1
EPB41L5EPB41L5erythrocyte membrane protein band 4.1 like 5
SERPINE2SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

Troyanskaya Laboratory - Princeton University