ASD

GO:0070918 production of small RNA involved in gene silencing by RNA (15)

GeneInput weightStandardRank
AGO2--490
ZCCHC11--737
DICER1--1762
SMAD3--823
SMAD1--1872
SMAD2--2694
LIN28B--5378
LIN28A--7070
DGCR8--8286
PRKRA--9728
SRRT--12400
SNIP1--12657
DROSHA--14199
RBM3--22670
TARBP2--24667

Network

GO:0070918

Network
Enrichment
NameDescriptionExternal IDs
AGO2argonaute RISC catalytic component 2 Entrez:27161  HGNC: 3263  HPRD: 06943  Ensembl: ENSG00000123908 
ZCCHC11zinc finger, CCHC domain containing 11 Entrez:23318  HGNC: 28981  Ensembl: ENSG00000134744  HPRD: 15700 
DICER1dicer 1, ribonuclease type III Entrez:23405  HGNC: 17098  Ensembl: ENSG00000100697  HPRD: 05875 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
SMAD1SMAD family member 1 Entrez:4086  Ensembl: ENSG00000170365  HGNC: 6767  HPRD: 03356 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
AGO2argonaute RISC catalytic component 2
ZCCHC11zinc finger, CCHC domain containing 11
DICER1dicer 1, ribonuclease type III
SMAD3SMAD family member 3
SMAD1SMAD family member 1
Query geneGeneGene descriptionEdge score
AGO2AGO2argonaute RISC catalytic component 2
ZCCHC11ZCCHC11zinc finger, CCHC domain containing 11
DICER1DICER1dicer 1, ribonuclease type III
SMAD3SMAD3SMAD family member 3
SMAD1SMAD1SMAD family member 1

Troyanskaya Laboratory - Princeton University