ASD

GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway (18)

GeneInput weightStandardRank
FBXW7--198
ADORA1--960
ADRA2A0.2511399
ESR10.2511791
TGFA--1873
PDE6H--4126
ADAM17--5323
FASLG--15523
ADRA2C--8551
NUP62--18755
EREG--9052
GPER1--9912
ADRA2B--10119
AFAP1L2--10424
EPGN--12503
EGF0.25112881
AGT--113305
PDE6G--120364

Network

GO:0045742

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
ESR1estrogen receptor 1 Entrez:2099  HGNC: 3467  HPRD: 00589  Ensembl: ENSG00000091831 
TGFAtransforming growth factor, alpha Entrez:7039  HPRD: 07522  HGNC: 11765  Ensembl: ENSG00000163235 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ADORA1adenosine A1 receptor
ADRA2Aadrenoceptor alpha 2A
ESR1estrogen receptor 1
TGFAtransforming growth factor, alpha
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ADORA1ADORA1adenosine A1 receptor
ADRA2AADRA2Aadrenoceptor alpha 2A
ESR1ESR1estrogen receptor 1
TGFATGFAtransforming growth factor, alpha

Troyanskaya Laboratory - Princeton University