ASD

GO:0030517 negative regulation of axon extension (13)

GeneInput weightStandardRank
BCL11A1.0132
SLIT1--61
SEMA4F--303
RNF6--12235
RTN4--2735
NRP1--2807
WNT5A--3319
SEMA3A--3494
TNR--3868
WNT3--4613
WNT3A--4747
RYK--5383
NTN1--6023

Network

GO:0030517

Network
Enrichment
NameDescriptionExternal IDs
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein) Entrez:53335  Ensembl: ENSG00000119866  HGNC: 13221  HPRD: 05949 
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F Entrez:10505  HGNC: 10734  HPRD: 04748 
RNF6ring finger protein (C3H2C3 type) 6 Entrez:6049  HGNC: 10069  Ensembl: ENSG00000127870  HPRD: 05027 
RTN4reticulon 4 Entrez:57142  Ensembl: ENSG00000115310  HGNC: 14085  HPRD: 07259 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
SLIT1slit homolog 1 (Drosophila)
SEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
RNF6ring finger protein (C3H2C3 type) 6
RTN4reticulon 4
Query geneGeneGene descriptionEdge score
BCL11ABCL11AB-cell CLL/lymphoma 11A (zinc finger protein)
SLIT1SLIT1slit homolog 1 (Drosophila)
SEMA4FSEMA4Fsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
RNF6RNF6ring finger protein (C3H2C3 type) 6
RTN4RTN4reticulon 4

Troyanskaya Laboratory - Princeton University