ASD

GO:0030802 regulation of cyclic nucleotide biosynthetic process (132)

GeneInput weightStandardRank
GABBR20.25142
NTRK20.25151
ADNP1.0171
GRM70.251137
ADCY2--175
GNAQ--189
ADCYAP1--230
SSTR2--251
GABBR10.251264
NF10.251372
ADCY10.251466
CRHR1--589
APLP1--591
GRM3--652
GNAZ--856
DRD10.251899
ADORA1--960
OPRK10.251996
CALCA--1013
NPY2R0.2511024
ADRB1--1057
DRD50.2511103
GNAL--1177
NPY1R0.2511190
GRIK30.2511247
GUCA1A--11258
GNAI3--1262
ADCYAP1R1--1273
FSHR--11398
ADRA2A0.2511399
GRM80.2511404
GNAI1--1468
PALM--1501
CAP2--1512
GRM2--1757
AKAP5--1759
VIPR2--1823
GNAS--11842
ADCY9--1850
SPECC1L--1912
PTHLH--11993
GUCY1A3--1997
EDNRB--12042
HTR70.2512365
CALCR--2381
CAP1--2541
ADCY8--2785
ADCY6--2877
MCHR10.2512905
ADRB3--12953
LHCGR0.2513057
HTR1A0.2513315
TSHR--3382
CHRM50.2513694
DRD20.2513749
RXFP1--3767
MC2R--3795
GNG7--3815
AKAP12--3839
MC4R0.2513850
EDNRA--13857
GSK3A--4141
HTR4--4168
GHRHR--4237
FLNA--14285
ADCY5--4295
S1PR1--4301
P2RY1--4342
DRD30.2514349
CALCRL0.2514392
ABCA1--14703
MC5R--4977
GCG--5190
MRAP2--5265
GPR3--5301
NPR3--5370
CHRM4--5408
ADCY3--5755
GNAI2--5860
RXFP2--15887
GALR1--5908
ACR--6002
OPRD10.2516030
OPRL10.2516271
GNA13--6683
ADORA3--6739
S1PR3--6774
GCGR--16828
PTH--6947
DRD40.2517021
AVPR2--17031
GRM4--7321
GHRH--7478
MC1R--17999
HTR1B0.2518092
MC3R0.2518188
GPR26--8197
ADORA2A0.2518408
NTRK10.2518522
ADCY4--9091
NPPC--9349
EDN1--9540
GLP1R--9893
GUCA2B--10165
GIPR--10369
RGS1--10535
UCN3--10665
MRAP--10905
PTGDR2--10914
PDZD3--11066
GUCA1B--12297
CORT--12689
AVP--113439
SSTR50.25114876
GALR2--14926
LTB4R2--15126
ADM2--15255
GALR3--15691
INSL3--119059
ADORA2B--19522
NOS3--20542
P2RY11--20669
OXER1--20906
GPR78--20984
SLC9A3R1--21898
S1PR4--22105
GPR65--22555
ADRB20.25123251
CCR2--23296
APOE0.25123516
NPR1--24948
ADCY7--25408

Network

GO:0030802

Network
Enrichment
NameDescriptionExternal IDs
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2 Entrez:9568  Ensembl: ENSG00000136928  HGNC: 4507  HPRD: 09552 
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  Ensembl: ENSG00000101126  HPRD: 09793  HGNC: 15766 
GRM7glutamate receptor, metabotropic 7 Entrez:2917  HGNC: 4599  Ensembl: ENSG00000196277  HPRD: 04979 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
NTRK2neurotrophic tyrosine kinase, receptor, type 2
ADNPactivity-dependent neuroprotector homeobox
GRM7glutamate receptor, metabotropic 7
ADCY2adenylate cyclase 2 (brain)
Query geneGeneGene descriptionEdge score
GABBR2GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
ADNPADNPactivity-dependent neuroprotector homeobox
GRM7GRM7glutamate receptor, metabotropic 7
ADCY2ADCY2adenylate cyclase 2 (brain)

Troyanskaya Laboratory - Princeton University