ASD

GO:0007172 signal complex assembly (24)

GeneInput weightStandardRank
GRIK20.51232
MAGI2--255
CACNA1A--1270
DLG20.251328
MAPK8IP2--418
GRIN2B1.01763
DLG4--857
GRIK5--1396
LRP4--1500
PTK20.2512488
SRC--2825
PTK2B--3063
NCK2--3077
CDK50.2513194
MUSK--4006
FLNA--14285
AGRN0.2516010
PXN--6823
CD3E--9680
SMO0.25110504
PICK1--11315
NCK1--12890
DVL1P1--18731
DVL1--18924

Network

GO:0007172

Network
Enrichment
NameDescriptionExternal IDs
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2 Entrez:9863  Ensembl: ENSG00000187391  HGNC: 18957  HPRD: 16212 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
DLG2discs, large homolog 2 (Drosophila) Entrez:1740  Ensembl: ENSG00000150672  HGNC: 2901  HPRD: 08220 
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIK2glutamate receptor, ionotropic, kainate 2
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
DLG2discs, large homolog 2 (Drosophila)
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
Query geneGeneGene descriptionEdge score
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
MAGI2MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 2
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
DLG2DLG2discs, large homolog 2 (Drosophila)
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2

Troyanskaya Laboratory - Princeton University