ASD

GO:0043434 response to peptide hormone stimulus (354)

GeneInput weightStandardRank
GNB1--24
PLCB1--148
KRAS--157
YWHAB0.251107
PIK3R10.251150
ADCY2--175
FGFR2--1237
IGF1R--252
GNB2--258
FGF9--262
ATP6V0B--277
ATP6V1G2--367
MAP1B--403
ABCC8--1406
GNG4--457
ADCY10.251466
NR3C1--496
ATP6V0C0.251502
ATP6V0D1--539
SHC3--559
PRKCI--568
VLDLR0.251574
PRKACB--584
GRIN2B1.01763
CCND2--782
TSC10.251790
CCKBR--794
CAB39--797
SOS1--1810
ATP6V1A--886
PCSK1--898
DRD10.251899
MAP2K10.251907
GNG3--927
FYN--932
NR4A3--1963
BTG1--1000
AKT10.2511020
FOXO3--1056
HIF1A--1075
MAPK1--1128
RELA--1142
GAB1--1198
MAP2K20.2511240
PRKAR1B--1257
DLC1--1282
PKM--1291
IRS2--11300
ERBB3--1350
BAIAP20.2511353
PIK3CA0.2511362
IRS1--11374
RPS6KB1--1521
JUNB--1547
SMARCC1--1678
PDPK1--1740
GNG13--1774
VGF0.2511782
ATP6V1B2--1815
BSG--1821
GNAS--11842
CDO1--1847
ADCY9--1850
FGF1--1892
AR0.2511902
GRB10--1910
PTPRN--1921
HDAC5--1950
PIK3R3--1966
ATP6V0A1--2034
PRKAB2--2067
PPM1A--2070
PRKAR2B--2211
SHC2--2256
FGFR1--2262
NR0B1--12278
FGF5--2327
ATP6V1F--2424
PRKAR1A--12428
GHSR0.2512467
BCL20.2512485
PTK20.2512488
FGF7--2591
STAT5B--2593
SOCS7--2602
FGFR3--12640
FOXA2--2645
GCK--12660
SCAP--2683
CRK--2713
ADCY8--2785
INHBB--2842
ADCY6--2877
CFTR--12951
GRB2--2962
BTG2--3036
EGR1--3062
CITED1--3064
ALDOB--3137
STC2--3169
STS0.2513198
HDAC9--3228
RAF10.2513236
EIF4G1--3374
MAX--3376
RBP4--3448
DAG1--3580
RHEB--3728
GNG2--3743
GNG7--3815
PDE3B--3819
MC4R0.2513850
FGF23--13888
PRKAA2--3894
AKT2--13912
KL--3938
FOXO10.2513947
ACVR1C--3963
UBE2B--4057
ATP6V1E1--4070
AKAP1--4078
LPIN1--4092
PRKACG--4112
ABCC5--4120
GSK3A--4141
FABP30.2514154
PPARA--4177
PRKAG2--14212
GHRHR--4237
MAS1--4244
FGF20--4263
AP3S1--4280
ADCY5--4295
GPAM--4380
WNT1--4383
OTC--14449
EIF4E0.2514457
FGF10--14532
SLC2A2--4553
ATP6V1G1--4576
SH2B2--4634
NKX6-1--4665
INPPL1--4681
FGF3--4687
TH0.2514933
FGF4--4938
PAK1--4940
SRD5A10.2514966
MLST8--5028
FGF17--5072
HRAS0.2515086
POR0.2515184
GCG--5190
PIK3R2--5198
CAPN10--5208
ATP6V1H--5369
AANAT0.2515448
F7--5465
LDLR--5488
PNLIPRP1--5719
PNLIP--5747
ADCY3--5755
INSR--15872
IGFBP1--5873
GNG8--5935
STK11--16000
ADIPOQ0.2516032
PLA2G1B--6059
PIK3R4--6073
ENPP1--16091
SERPINA7--6130
ATP6V1D--6195
NGF0.2516229
EGR20.2516247
GIP--6352
STRADA--6362
SI--6367
SOCS2--6371
FGF18--6382
OXTR0.516388
ATP6V1G3--6391
SORBS1--6411
MAPK30.2516426
GNG5--6755
PXN--6823
GCGR--16828
GALP--7001
TRPV10.2517162
FRS2--7173
PHIP--7304
SFRP4--7310
NPPB--7334
ATP6V0A4--7653
PTPN11--17735
CXCL12--7802
GH1--7858
MET1.018002
PCK1--8020
CYP11A10.2518063
GNB3--18308
ATP6V1C2--8391
FGF16--8467
TIMP1--8520
STAT3--18538
FGF8--18543
GSTP10.2518742
UCP3--18932
EREG--9052
ADCY4--9091
STXBP4--9119
ATP6V0D2--9130
KLB--9187
NPPA--19231
TSC20.2519351
PIK3C3--9358
FOXO4--9362
AQP2--9426
IL10--19513
SOCS1--9583
PRKACA--9630
HSD11B2--9892
PKLR--9956
ATP6V0E2--10017
SHC1--10045
GHR--110098
APPL1--10112
FOXC2--10175
INSIG2--10252
GNG12--10259
PRKAG3--10274
LYN--10336
PFKFB1--10385
DBH0.25110495
ATP6V0A2--10497
KHK--10546
ATP6V1B1--10564
CAB39L--10629
PCSK9--10760
BRAF--111149
OXT0.25111176
PTPN2--11261
PRKAR2A--11450
AHSG--11515
PIK3CB--11542
IRF1--111641
LEP0.25111864
BCAR1--12026
HMGCS2--12061
FGF19--12130
ATP6V1E2--12277
GATM--112279
RXRA0.25112299
APOBEC1--12314
IL6--112695
USF1--12725
ZNF106--12789
TLR4--112795
CPS1--112820
RETN0.25112871
TFF1--13131
FGF2--13150
FGF22--13277
TLR9--13360
CYP21A20.25113362
GJA10.25113867
GAL--13897
TFF3--13944
RHOQ--14092
NRAS--114119
RPTOR--14284
QDPR0.25114344
SORT1--14441
FOXO6--14502
EIF4EBP2--14825
FGF6--15185
PRKCQ--15381
GNB4--16807
FZD2--16930
SLC2A8--19364
SREBF1--19464
ARG1--119499
HHEX--19523
CACYBP--19557
JAK2--119561
IL6R--19897
TIMP4--20100
FOXS1--20143
FADS1--20470
NOS3--20542
FZD1--20775
TRIB3--20863
PDGFB--21071
MTOR--21095
ADM--21106
SLC27A1--21124
STAT5A--21176
PRKAB1--21601
ATP6V1C1--21645
UCP2--21958
INS--122047
PLD1--22064
FBP1--122125
GNG10--22178
EIF4B--22190
IGF20.25122401
PLAT--22444
SOCS3--22661
CYC1--22672
PPARG--122729
EIF4EBP1--22803
ANXA10.5122810
TRIM16--22841
PLD2--22908
PRKAA1--22917
CCL5--23042
SLC29A2--23071
LTA4H--23171
TCIRG1--123264
BDH1--23265
EIF2B1--23375
NUDC--23418
GGH--23462
STRADB--23510
KAT2B--23529
CTGF--23607
ACSL5--23792
PARP1--23828
PRSS8--23956
FGFR4--23965
THEM4--24011
IL18--24018
INPP5K--24055
GNG11--24075
COL1A1--124140
EEF2K--24194
ASS1--124321
PRKAG1--24404
PRKDC--24421
EIF2B4--24428
GOT1--24441
FAS--124697
DOK1--24800
NR1H3--25006
CDK1--25053
EIF2B5--25325
HADH--125329
EIF2B2--25351
SPARC--25365
ADCY7--25408
EIF2B3--25449
ATP6V0E1--25547
PPAT--25601
CTSB--25627
RPS6--25698

Network

GO:0043434

Network
Enrichment
NameDescriptionExternal IDs
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
KRASKirsten rat sarcoma viral oncogene homolog
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Query geneGeneGene descriptionEdge score
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
KRASKRASKirsten rat sarcoma viral oncogene homolog
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Troyanskaya Laboratory - Princeton University