ASD

GO:0001702 gastrulation with mouth forming second (25)

GeneInput weightStandardRank
LRP6--279
SMAD4--821
CHRD--941
AMOT--1325
OTX2--11916
TENM4--2243
LHX1--2560
FOXA2--2645
SRF--2841
NODAL--13149
T--3286
WNT5A--3319
ACVR1--16054
RNF2--7154
FRS2--7173
CTNNB10.519066
LRP5--19420
PPAP2B--10628
LDB1--10693
GDF3--110819
NAT8B--12318
GATA4--112466
NAT8--12874
NSD10.25114116
UGDH--21580

Network

GO:0001702

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
CHRDchordin Entrez:8646  Ensembl: ENSG00000090539  HGNC: 1949  HPRD: 04592 
AMOTangiomotin Entrez:154796  HGNC: 17810  Ensembl: ENSG00000126016  HPRD: 02327 
OTX2orthodenticle homeobox 2 Entrez:5015  HGNC: 8522  HPRD: 07190  Ensembl: ENSG00000165588 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
SMAD4SMAD family member 4
CHRDchordin
AMOTangiomotin
OTX2orthodenticle homeobox 2
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
SMAD4SMAD4SMAD family member 4
CHRDCHRDchordin
AMOTAMOTangiomotin
OTX2OTX2orthodenticle homeobox 2

Troyanskaya Laboratory - Princeton University