ASD

GO:0051896 regulation of protein kinase B signaling cascade (54)

GeneInput weightStandardRank
IGF1R--252
RICTOR--537
PTEN1.011389
SPRY2--1454
MTDH--1461
ITSN1--1789
GATA3--2376
EGFR--12546
IGF10.2512793
IGFBP5--3306
TSPYL5--3354
TCF7L20.513548
DAG1--3580
KLF4--3609
PDGFA--3731
DRD20.2513749
NOX4--3804
HBEGF--3865
PLEKHA1--3930
ANGPT1--4182
DRD30.2514349
TNFSF11--15271
TEK--5322
F7--5465
RASD2--5562
INSR--15872
STK11--16000
TGFBR1--17268
ILK--7305
MC1R--17999
PTPRJ--19136
TSC20.2519351
ARRB2--10647
F3--10889
SFRP5--11273
GPX10.25111644
IL26--11645
VEGFB--11980
IL6--112695
CCL19--14578
ZP3--17443
EPHA2--119467
TGFB10.25120135
MTOR--21095
KIAA1161--21137
ADAM8--21797
CCL21--21829
SLC9A3R1--21898
INS--122047
F10--22126
CCR7--22367
IGF20.25122401
THBS1--24444
PHLDA3--24856

Network

GO:0051896

Network
Enrichment
NameDescriptionExternal IDs
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
RICTORRPTOR independent companion of MTOR, complex 2 Entrez:253260  HGNC: 28611  HPRD: 10682  Ensembl: ENSG00000164327 
PTENphosphatase and tensin homolog Entrez:5728  HGNC: 9588  HPRD: 03431 
SPRY2sprouty homolog 2 (Drosophila) Entrez:10253  Ensembl: ENSG00000136158  HPRD: 03916  HGNC: 11270 
MTDHmetadherin Entrez:92140  Ensembl: ENSG00000147649  HGNC: 29608  HPRD: 17459 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
IGF1Rinsulin-like growth factor 1 receptor
RICTORRPTOR independent companion of MTOR, complex 2
PTENphosphatase and tensin homolog
SPRY2sprouty homolog 2 (Drosophila)
MTDHmetadherin
Query geneGeneGene descriptionEdge score
IGF1RIGF1Rinsulin-like growth factor 1 receptor
RICTORRICTORRPTOR independent companion of MTOR, complex 2
PTENPTENphosphatase and tensin homolog
SPRY2SPRY2sprouty homolog 2 (Drosophila)
MTDHMTDHmetadherin

Troyanskaya Laboratory - Princeton University