ASD

GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process (8)

GeneInput weightStandardRank
FBXW7--198
PTEN1.011389
WNT1--4383
AXIN1--14419
PSEN1--18523
FBXO22--23669
PML--25277
CLU--25437

Network

GO:2000058

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
PTENphosphatase and tensin homolog Entrez:5728  HGNC: 9588  HPRD: 03431 
WNT1wingless-type MMTV integration site family, member 1 Entrez:7471  HGNC: 12774  HPRD: 01276 
AXIN1axin 1 Entrez:8312  HPRD: 04819  Ensembl: ENSG00000103126  HGNC: 903 
PSEN1presenilin 1 Entrez:5663  HPRD: 00087  HGNC: 9508  Ensembl: ENSG00000080815 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
PTENphosphatase and tensin homolog
WNT1wingless-type MMTV integration site family, member 1
AXIN1axin 1
PSEN1presenilin 1
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
PTENPTENphosphatase and tensin homolog
WNT1WNT1wingless-type MMTV integration site family, member 1
AXIN1AXIN1axin 1
PSEN1PSEN1presenilin 1

Troyanskaya Laboratory - Princeton University