ASD

GO:0030168 platelet activation (241)

GeneInput weightStandardRank
ATP2B20.513
GNB1--24
ATP2B1--105
PIK3R10.251150
GNAQ--189
KCNMA10.251191
PRKCE--204
ATP2B3--209
YWHAZ0.251269
SLC8A2--334
CALM3--352
DGKZ--547
PFN1--548
ITPR1--1597
ATP2A2--1690
STXBP1--769
ACTN2--1792
KCNMB2--804
TGFB2--834
NOS10.251853
GUCY1B3--873
FYN--932
SCG3--979
PRKCZ--991
AKT10.2511020
PRKCA--1027
CALM1--1029
DGKI--1124
MAPK1--1128
PRKCB0.511186
TRPC3--1196
CX3CL1--1199
PDE10A--1201
GNAI3--1262
DGKB--1341
PIK3CA0.2511362
GNAI1--1468
PRKCG--11483
APP--1515
SLC8A1--1529
PRKG1--1553
RAC1--1617
PDPK1--1740
KCNMB4--1767
GNAS--11842
PDE2A--1938
PIK3R3--1966
PDE1A--1968
GUCY1A3--1997
TYRO3--2083
GUCY1A2--2093
DGKG--2155
GNA11--2281
RHOA--2292
TRPC7--2516
PDE1B--2534
CAP1--2541
ACTN4--12685
SOD1--12702
LRP8--2732
ALDOA0.2512739
PDE11A--2780
IGF10.2512793
THPO--12812
CALM2--2814
SRC--2825
GP5--2844
VAV2--2850
VAV3--2908
TRPC60.512954
RASGRP10.2513043
HRG--3052
BRPF3--3105
RHOB--3118
ATP2B4--3217
RAF10.2513236
PDE3A--3628
GNA14--3634
DGKE--3651
PDE9A--3656
PDGFA--3731
GNG2--3743
PDE3B--3819
PPIA--3877
PRKG2--3879
MAPK14--3975
WDR1--4062
VEGFA0.2514087
SLC8A3--4131
CFL1--4162
HABP4--4211
FLNA--14285
P2RY1--4342
MPL--14359
MRVI1--4526
TF--14527
ALB--4667
P2RY12--4729
WNT3A--4747
DGKD--4786
F2RL2--4805
DAGLA--5115
PIK3R2--5198
HGF0.2515313
TTN--15620
PDE5A--5684
ACTN1--5704
GNAI2--5860
RHOG--6279
TMSB4X--6302
GP6--6406
MAPK30.2516426
PRKCD--6504
DGKH--6642
GNA13--6683
FIGF--6702
KNG1--6802
MERTK--6878
TUBA4A--7023
LEFTY2--7335
CD40LG--7577
ADAMTS13--7680
IL11--7718
PTPN11--17735
KCNMB3--7769
ITPR2--8066
PDE6B--18154
TIMP1--8520
APOB--8737
ENTPD2--8946
PLG--9166
FGA--19461
FGB--19587
F2RL3--9626
MMRN1--9870
DGKQ--9874
PDE6A--10187
KCNMB1--10263
PIK3CG0.25110306
LYN--10336
F5--110577
ARRB2--10647
CD63--10861
TLN1--10904
PIK3CB--11542
NOS20.25111577
PSAP--11767
RASGRP2--11775
TREML1--11807
ITGB30.5111817
PRKCH--111853
VEGFB--11980
PPBP--12054
GP9--112359
IL6--112695
VEGFC--12850
EGF0.25112881
TGFB3--113097
SELP--13751
STX4--13828
GUCY1B2--14094
MGLL--14193
GNA12--14481
BLOC1S3--14755
VWF--115129
GP1BB--115143
PRKCQ--15381
FERMT3--115639
FGG--15642
DGKK--16992
PF4--17209
STIM1--17385
F2--118599
SERPINF2--18906
APOA1--118958
HSPA5--19143
P2RX1--19303
TBXA2R--19479
PIK3R5--19487
PIK3R6--19802
ARRB1--19906
FZD6--19921
F2R--20036
TGFB10.25120135
PDE6G--120364
F13A1--120377
NOS3--20542
DAGLB--20569
VCL--120732
ORAI1--20789
GNA15--20926
LAT--20987
ATP2A3--20997
PDGFB--21071
F8--21169
SRGN--21336
FCER1G--21507
POTEKP--21513
PTGIR0.25121564
ITPR3--21697
ITGA2B--121808
FGR--21869
ATP2A1--122234
SERPINA1--122405
SAA1--22464
COL1A2--122629
PLA2G4A--22727
GATA1--122759
COL3A1--122855
CD9--22906
DGKA--23016
GP1BA--123019
CFD--23364
LCP2--23508
CD36--23662
PECAM10.25123800
VAV1--23876
SYK--23906
ABCC4--23966
A2M--24058
COL1A1--124140
SAA2--24171
PTPN6--24184
PLEK--24240
THBS1--24444
FN1--24517
AXL--24522
CALU--24558
PLCG2--24731
LCK--24753
RAC2--24787
PLSCR1--24943
SERPINE10.25125055
SERPING1--125126
STXBP3--25176
CD40--25231
SPARC--25365
CLU--25437
GAS6--25481
PROS1--25655
LAMP2--125700

Network

GO:0030168

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
ATP2B1ATPase, Ca++ transporting, plasma membrane 1 Entrez:490  Ensembl: ENSG00000070961  HGNC: 814  HPRD: 00158 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
ATP2B1ATPase, Ca++ transporting, plasma membrane 1
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
GNAQguanine nucleotide binding protein (G protein), q polypeptide
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
ATP2B1ATP2B1ATPase, Ca++ transporting, plasma membrane 1
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide

Troyanskaya Laboratory - Princeton University