ASD

GO:0048261 negative regulation of receptor-mediated endocytosis (7)

GeneInput weightStandardRank
RAC1--1617
PICALM--12597
ARF6--3317
MTMR2--113176
APOC2--13818
APOC3--20262
APOC1--23668

Network

GO:0048261

Network
Enrichment
NameDescriptionExternal IDs
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
PICALMphosphatidylinositol binding clathrin assembly protein Entrez:8301  Ensembl: ENSG00000073921  HPRD: 04320  HGNC: 15514 
ARF6ADP-ribosylation factor 6 Entrez:382  HGNC: 659  HPRD: 02714 
MTMR2myotubularin related protein 2 Entrez:8898  Ensembl: ENSG00000087053  HGNC: 7450  HPRD: 04650 
APOC2apolipoprotein C-II Entrez:344  HPRD: 07457  HGNC: 609 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
PICALMphosphatidylinositol binding clathrin assembly protein
ARF6ADP-ribosylation factor 6
MTMR2myotubularin related protein 2
APOC2apolipoprotein C-II
Query geneGeneGene descriptionEdge score
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
PICALMPICALMphosphatidylinositol binding clathrin assembly protein
ARF6ARF6ADP-ribosylation factor 6
MTMR2MTMR2myotubularin related protein 2
APOC2APOC2apolipoprotein C-II

Troyanskaya Laboratory - Princeton University