ASD

GO:0045668 negative regulation of osteoblast differentiation (25)

GeneInput weightStandardRank
SFRP1--387
HDAC4--696
SMAD3--823
CHRD--941
CDK6--1795
ID2--2154
FGFR1--2262
NOTCH1--12865
SKI--2904
CITED1--3064
FGF23--13888
AXIN2--14260
MEN1--14917
NOG--15439
TWIST1--16980
ID1--9040
LRP5--19420
OSTN--10888
UCMA--13359
HDAC7--14702
TWIST2--15321
NBR1--22425
ID3--22679
C14orf169--23070
TWSG1--24840

Network

GO:0045668

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
CHRDchordin Entrez:8646  Ensembl: ENSG00000090539  HGNC: 1949  HPRD: 04592 
CDK6cyclin-dependent kinase 6 Entrez:1021  Ensembl: ENSG00000105810  HPRD: 04533  HGNC: 1777 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
HDAC4histone deacetylase 4
SMAD3SMAD family member 3
CHRDchordin
CDK6cyclin-dependent kinase 6
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
HDAC4HDAC4histone deacetylase 4
SMAD3SMAD3SMAD family member 3
CHRDCHRDchordin
CDK6CDK6cyclin-dependent kinase 6

Troyanskaya Laboratory - Princeton University