ASD

GO:0006576 cellular biogenic amine metabolic process (117)

GeneInput weightStandardRank
ATP2B20.513
GRIN2A0.25166
PAFAH1B10.25174
AZIN1--376
AMD1--664
SNCA--1667
TGFB2--834
DRD10.251899
PARK20.251952
NR4A20.251992
PNPLA6--11014
SNCAIP--1042
SNCB--11511
CHRNA70.511837
ACHE--2025
GATA3--2376
MTPN--2402
ASMTL--2405
ATP7A--12483
PDE1B--2534
FGF7--2591
CCBL1--2621
SLC5A7--2703
DHPS--2743
OAZ1--2789
BCHE--2809
PCYT1B--3239
MOXD1--3673
CDS1--3676
DRD20.2513749
CYP19A10.2513823
FABP30.2514154
AOC2--4339
OAZ2--4340
DRD30.2514349
PAH0.2514423
PON10.514541
CHKA--4706
TH0.2514933
SRD5A10.2514966
AGMAT--5224
AANAT0.2515448
ENPP6--5463
ENPP2--5528
TPH20.2515693
SMOX--5718
ACMSD--5793
DDC0.2515929
ADC--6046
PLA2G1B--6059
COLQ--6220
TPH10.2516460
DMGDH--6732
PLA2G5--6775
DRD40.2517021
CETP--7301
MRI1--7546
LRTOMT--17640
SLC6A30.517659
IDO2--7768
PNMT--8605
ENOPH1--9534
SMS--9865
DBH0.25110495
ASMT0.25110532
TDO20.25110565
CHAT--10603
SULT1B1--10710
PRG3--10802
EPAS1--10869
GCH10.25111867
LY6E--12003
LIPC--112083
ETNK2--12786
KMO--13147
COMT0.25113475
ODC1--113539
FABP50.25113633
AFMID--14135
APOA2--14659
HDC--15022
CHKB--17373
MOXD2P--17814
SAT1--17894
LPCAT2--17920
APOA1--118958
MAOA0.25119009
FABP5P3--19016
HAAO--19341
AADAT--19369
SULT1A3--20011
AGPAT6--20163
CHRFAM7A--20694
LUZP6--20893
LCAT--120976
SLC27A1--21124
SULT1A4--21342
SULT1A1--21610
SULT1A2--21810
MTAP--22001
PLA2G15--22188
APOA4--22292
PEMT--22436
PAOX--22526
KYNU--22720
PLA2G4A--22727
CCL5--23042
IDO1--23074
CCBL2--23177
APIP--23482
SRM--24301
GOT1--24441
ADI1--24626
NPR1--24948
ETNK1--25249
PCYT1A--25498
CHPT1--25553

Network

GO:0006576

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Entrez:5048  HGNC: 8574  HPRD: 03329  Ensembl: ENSG00000007168 
AZIN1antizyme inhibitor 1 Entrez:51582  HPRD: 07443  HGNC: 16432  Ensembl: ENSG00000155096 
AMD1adenosylmethionine decarboxylase 1 Entrez:262  HGNC: 457  Ensembl: ENSG00000123505  HPRD: 01622 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
AZIN1antizyme inhibitor 1
AMD1adenosylmethionine decarboxylase 1
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PAFAH1B1PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
AZIN1AZIN1antizyme inhibitor 1
AMD1AMD1adenosylmethionine decarboxylase 1

Troyanskaya Laboratory - Princeton University