ASD

GO:0031061 negative regulation of histone methylation (6)

GeneInput weightStandardRank
JARID2--946
BCOR--12290
PAX50.515041
DNMT1--13233
DNMT3B--14663
BRCA1--124573

Network

GO:0031061

Network
Enrichment
NameDescriptionExternal IDs
JARID2jumonji, AT rich interactive domain 2 Entrez:3720  HPRD: 03355  HGNC: 6196  Ensembl: ENSG00000008083 
BCORBCL6 corepressor Entrez:54880  HGNC: 20893  Ensembl: ENSG00000183337  HPRD: 06458 
PAX5paired box 5 Entrez:5079  HPRD: 01334  HGNC: 8619  Ensembl: ENSG00000196092 
DNMT1DNA (cytosine-5-)-methyltransferase 1 Entrez:1786  HPRD: 00532  HGNC: 2976  Ensembl: ENSG00000130816 
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta Entrez:1789  HPRD: 04209  HGNC: 2979  Ensembl: ENSG00000088305 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
JARID2jumonji, AT rich interactive domain 2
BCORBCL6 corepressor
PAX5paired box 5
DNMT1DNA (cytosine-5-)-methyltransferase 1
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta
Query geneGeneGene descriptionEdge score
JARID2JARID2jumonji, AT rich interactive domain 2
BCORBCORBCL6 corepressor
PAX5PAX5paired box 5
DNMT1DNMT1DNA (cytosine-5-)-methyltransferase 1
DNMT3BDNMT3BDNA (cytosine-5-)-methyltransferase 3 beta

Troyanskaya Laboratory - Princeton University