ASD

GO:0000209 protein polyubiquitination (156)

GeneInput weightStandardRank
PSMA1--58
TTC3--68
PSMD14--104
PSMA4--166
UBR5--193
PSMB3--234
PSMA5--284
UBE3A0.251365
PSMD8--371
PSMA3--460
PSMB1--501
UBE2D3--528
PSMC6--679
PSMD6--688
UBE2N--734
UBE2D2--735
NPEPPS--739
PSMB7--745
MARCH6--751
PSME4--787
PSMC2--815
FBXW11--859
PARK20.251952
PSMD11--967
RNF4--973
PSMB4--1091
PSMD1--1168
PSMA7--1174
UBE2E3--1210
PSMC4--1269
PSMC1--1296
UBE2G1--1334
TNKS--1414
PSMA6--1510
PSMD12--1573
UBE2R2--1579
CDC34--1592
RNF41--1596
PSMB6--1607
PSMD2--1706
ZFP91--1788
UBE2K--1834
BTRC--1884
PSMC5--1897
UBE2V2--1939
PSMD3--2008
UBE2S--2043
UBE4B--2086
PSMD4--2087
UBE2W--2180
RNF6--12235
PSMC3--2240
PSMD10--2412
PSMD7--2481
BCL20.2512485
DZIP3--2653
PSMA2--2699
FZR1--2920
ITCH--2932
UBE2A0.2513019
PSMD13--3051
SMURF1--3060
HUWE1--3292
MAP3K1--13381
RNF152--3719
UBE2B--4057
STUB1--4250
UBE2L3--4335
TNKS2--4385
TNFAIP3--4469
ARIH2--4649
UBE2Q2--4678
ANAPC2--5008
UBE2G2--5131
BARD1--15343
UBE4A--5572
UBE2H0.2515792
MARCH5--6331
MARCH1--6624
UBC--6756
RNF5--7182
UBE3C--7351
TPP2--7759
RNF146--7910
UBE2E1--7950
ZSWIM2--8496
BIRC2--9515
CDC27--9665
TRIM320.2519794
PSMA8--10087
UBE2V1--11027
TRAF6--11055
BLMH--11539
WWP2--11885
PSMB2--11986
PSMB11--12480
RNF31--12873
UBOX5--13002
LRSAM1--13116
NHLRC1--113198
RNF168--13760
PSMD9--13911
RNF167--14002
NEDD40.25114040
ANAPC13--14246
PSME2--14327
UBE2E2--14530
CDC23--14728
ANAPC11--14928
LNPEP--15859
PPIL2--16594
HDAC6--16779
RNF216--17136
TRIM56--18214
ZNF738--19419
UBB--19448
PSMD5--19823
FBXO4--20319
RNF187--20424
CHFR--20544
CDKN2A--120587
ERCC8--120608
G2E3--20704
AMFR--20817
PSME1--21072
MARCH8--21098
ANAPC10--21179
RNF20--21249
PSMB9--21373
PSMB10--21853
PSMB8--22146
PSME3--22162
CDC26--22265
PSMF1--22424
RBCK1--22556
SHARPIN--22710
PRPF19--22991
FBXO22--23669
TRAF2--23686
RPS27A--24381
UBA52--24384
ANAPC4--24419
UBE2D4--24492
BRCA1--124573
ANAPC7--24632
TRIM21--24895
UBE2D1--24988
CDC16--24989
ANAPC1--25203
DTL--25229
PSMB5--25250
UBE2T--25295
DDB2--125337
ANAPC5--25367
SKP2--25574
UBE2C--25614

Network

GO:0000209

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
TTC3tetratricopeptide repeat domain 3 Entrez:7267  HPRD: 03773  HGNC: 12393  Ensembl: ENSG00000182670 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
UBR5ubiquitin protein ligase E3 component n-recognin 5 Entrez:51366  HPRD: 06436  Ensembl: ENSG00000104517  HGNC: 16806 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
TTC3tetratricopeptide repeat domain 3
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
UBR5ubiquitin protein ligase E3 component n-recognin 5
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
TTC3TTC3tetratricopeptide repeat domain 3
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
UBR5UBR5ubiquitin protein ligase E3 component n-recognin 5

Troyanskaya Laboratory - Princeton University