ASD

GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (50)

GeneInput weightStandardRank
CNOT4--197
DCP2--713
CNOT7--799
CNOT3--1200
LSM3--1525
CNOT6--1567
PAIP1--1686
CNOT2--1840
PAN3--2201
CNOT8--2401
ZFP36L2--2493
EIF4A2--2547
DCP1A--2719
DDX6--2843
ZFP36L1--3125
EIF4G1--3374
EIF4A1--3451
EDC4--3532
CNOT1--3966
LSM4--4015
CNOT6L--4369
EIF4E0.2514457
EXOSC8--4830
DIS3--5355
XRN1--7076
PATL1--8983
PABPC1--9200
LSM2--10522
TNKS1BP1--10560
LSM5--10699
PAN2--10916
LSM1--12104
RQCD1--12325
LSM6--15661
EDC3--19616
EXOSC6--20114
EXOSC1--20963
DCP1B--22040
EIF4B--22190
EXOSC4--23255
DCPS--24092
CNOT11--24097
CNOT10--24190
EXOSC9--24287
EXOSC7--24964
PARN--25199
EXOSC5--25487
MLH1--125513
EXOSC3--25551
EXOSC2--25651

Network

GO:0000288

Network
Enrichment
NameDescriptionExternal IDs
CNOT4CCR4-NOT transcription complex, subunit 4 Entrez:4850  HGNC: 7880  HPRD: 05369  Ensembl: ENSG00000080802 
DCP2decapping mRNA 2 Entrez:167227  HPRD: 13125  Ensembl: ENSG00000172795  HGNC: 24452 
CNOT7CCR4-NOT transcription complex, subunit 7 Entrez:29883  Ensembl: ENSG00000198791  HGNC: 14101 
CNOT3CCR4-NOT transcription complex, subunit 3 Entrez:4849  HPRD: 05368  HGNC: 7879  Ensembl: ENSG00000088038 
LSM3LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) Entrez:27258  HGNC: 17874  HPRD: 06283 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNOT4CCR4-NOT transcription complex, subunit 4
DCP2decapping mRNA 2
CNOT7CCR4-NOT transcription complex, subunit 7
CNOT3CCR4-NOT transcription complex, subunit 3
LSM3LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Query geneGeneGene descriptionEdge score
CNOT4CNOT4CCR4-NOT transcription complex, subunit 4
DCP2DCP2decapping mRNA 2
CNOT7CNOT7CCR4-NOT transcription complex, subunit 7
CNOT3CNOT3CCR4-NOT transcription complex, subunit 3
LSM3LSM3LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)

Troyanskaya Laboratory - Princeton University