ASD

GO:0014070 response to organic cyclic compound (216)

GeneInput weightStandardRank
GNAO1--4
CNR10.25129
GRIN2A0.25166
PRKCE--204
GABBR10.251264
GRIN1--294
SLC6A10.251313
EP300--1318
SFRP1--387
JUN--511
PPP2R2A--714
TAC10.251726
GRIN2B1.01763
CCND2--782
PCSK1--898
DRD10.251899
RYR2--1959
ACACA--1017
DRD50.2511103
RELA--1142
CDKN1B--1162
GNAL--1177
CHRNA3--1266
BAD--1290
NFIA--1486
LEF1--1499
WNT10B--1517
RPS6KB1--1521
JUNB--1547
FOS--1680
KCNK1--1751
NEDD8--1811
CHRNA70.511837
SMAD1--1872
BTRC--1884
STC1--1900
SPECC1L--1912
GUCY1A3--1997
ENO2--2103
DUSP6--2466
BCL20.2512485
DPYSL2--2672
RXRG0.2512866
PRL0.2512977
BTG2--3036
PTK2B--3063
ALDOB--3137
CDK50.2513194
STS0.2513198
TAC3--3251
WNT5A--3319
TRH--3416
FOXF1--13518
TACR3--3564
SMAD9--13672
DRD20.2513749
CYP19A10.2513823
GNAT3--3827
EDNRA--13857
PRKAA2--3894
HSP90AB1--3924
CYP17A10.2513984
ALDOC--4093
GSK3A--4141
AXIN2--14260
ABAT0.2514348
DRD30.2514349
AXIN1--14419
CHRNA40.2514471
FGF10--14532
RAE1--4538
IL1A--4651
NKX6-1--4665
PLCG1--4744
CHRNB4--4903
CD83--4926
TH0.2514933
ADRA1B0.2514946
SRD5A10.2514966
ACSL3--4998
TAT--15011
CYP1A10.2515067
PTGS20.2515085
SLC22A8--5281
PEA15--5442
AANAT0.2515448
F7--5465
CST3--15894
ADRBK1--6028
LGALS1--6065
NGF0.2516229
MSH2--16311
GIP--6352
OXTR0.516388
SLC18A2--6423
BMP4--16499
BCL2L1--6563
IL4--6852
DRD40.2517021
TGFBR1--17268
CYBA--17322
NPPB--7334
FOSL1--7629
SLC6A30.517659
CDKN1A--7714
HMGCS1--7719
SLC9A1--7776
CCND1--17970
MET1.018002
CYP11A10.2518063
HTR1B0.2518092
ADORA2A0.2518408
STAT3--18538
CTNNB10.519066
CEBPA--19079
AACS--9143
CTNNA1--9331
EDN1--9540
SLC7A11--9692
ASNS--9796
PKLR--9956
HSD17B30.2519988
SHC1--10045
GHR--110098
LYN--10336
DBH0.25110495
SLC22A6--10503
ANGPT2--10581
AMH--10601
TAF9B--10796
IL1B--110818
ALPL--110901
OXT0.25111176
TACR1--11618
PSMB2--11986
HMGCS2--12061
RXRA0.25112299
IL6--112695
IL13--12888
MMP14--12920
ATP12A--12962
AVP--113439
COMT0.25113475
CHRNA5--13636
SELP--13751
RYR1--113799
SDC20.25113950
FNTB--14256
OCLN--114257
CCL19--14578
CDKN2B--14806
BAG1--14923
TNF0.25115243
PRKCQ--15381
PEBP1--15772
CASP12--18416
ND1--18434
AHR--20015
TGFB10.25120135
CHRNB20.25120216
FADS1--20470
NOS3--20542
CHRFAM7A--20694
SRR--20837
BGLAP--20875
PDGFB--21071
CHURC1--21104
BAK1--21229
PLA2G4F--21292
HNMT--21489
CHRNB1--21815
ITGA6--22166
LONP2--22200
IGF20.25122401
SERPINA1--122405
TXN2--22459
UGT1A1--122467
SOCS3--22661
PPARG--122729
ANXA10.5122810
PLD2--22908
NCF2--122977
CCL5--23042
ALDH3A10.25123281
CTGF--23607
ICAM1--23720
FDX1--23764
TIMP3--23921
HMOX1--23938
CPT1A--23997
MGMT--24063
P2RY2--24088
ATF1--24277
CCNE1--24359
MMP9--24369
CDA--24491
CTSV--24505
UROD--124523
TAF2--24673
ADA0.5124751
LUM--24789
EPHX1--124841
CAD--24868
ACSL1--24993
CDK1--25053
SMPD1--125116
PLIN2--25164
CCNB1--25174
GPX3--25279
IL1RN0.25125385
MLH1--125513
FXN--125604
CTSB--25627
ACAT1--125641
CHEK1--25816
DHFR0.25125817

Network

GO:0014070

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1 Entrez:2550  HGNC: 4070  Ensembl: ENSG00000204681  HPRD: 04644 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1cannabinoid receptor 1 (brain)
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PRKCEprotein kinase C, epsilon
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1CNR1cannabinoid receptor 1 (brain)
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
PRKCEPRKCEprotein kinase C, epsilon
GABBR1GABBR1gamma-aminobutyric acid (GABA) B receptor, 1

Troyanskaya Laboratory - Princeton University