ASD

GO:0019882 antigen processing and presentation (126)

GeneInput weightStandardRank
PSMA1--58
PSMD14--104
PSMA4--166
PSMB3--234
PSMA5--284
PSMD8--371
PSMA3--460
PSMB1--501
BCAP31--620
PSMC6--679
PSMD6--688
NPEPPS--739
PSMB7--745
PSME4--787
PSMC2--815
PSMD11--967
PSMB4--1091
PSMD1--1168
PSMA7--1174
PSMC4--1269
PSMC1--1296
PSMA6--1510
PSMD12--1573
PSMB6--1607
PSMD2--1706
PSMC5--1897
PSMD3--2008
PSMD4--2087
PSMC3--2240
PSMD10--2412
PSMD7--2481
PSMA2--2699
ULBP1--2750
AP3D1--2891
UBE2A0.2513019
TAPBP--13023
PSMD13--3051
SEC24B--3534
SEC24C--3549
HLA-G--4467
CD1A--4623
HLA-C--4808
HLA-E--4817
HLA-F--5013
CD1B--5516
CLEC4M--5639
HLA-B0.2516387
MARCH1--6624
UBC--6756
HLA-DPB2--7607
TPP2--7759
CD1E--8663
PSMA8--10087
TAP1--110380
CTSE--10841
HLA-DRB5--10936
BLMH--11539
PSMB2--11986
SEC24A--12163
RAET1E--12464
PSMB11--12480
IFNG--112827
ULBP3--13137
HLA-DQB2--13605
CD209--13669
PSMD9--13911
PSME2--14327
HLA-H--14425
LNPEP--15859
CD1C--17969
CD8A--17983
MICA--18885
UBB--19448
HLA-A0.25119612
PSMD5--19823
RAET1G--20637
HLA-DRB3--20684
HLA-DRB4--20956
PSME1--21072
MARCH8--21098
SEC23A--21109
RAET1L--21183
PSMB9--21373
CD1D--21452
FCER1G--21507
HLA-DQA2--21718
HLA-DOB--21814
PDIA3--21841
PSMB10--21853
ERAP2--21994
HLA-DOA--22130
PSMB8--22146
CALR--22152
SEC24D--22153
B2M--22154
PSME3--22162
SEC31A--22244
AZGP1--22253
ULBP2--22254
PSMF1--22424
HLA-DQA1--122539
HLA-DPB1--22554
FCGRT--22744
HLA-DQB1--122976
HLA-DRA--23195
HLA-DRB10.25123273
SLC11A1--23561
SEC13--23717
ICAM1--23720
ERAP1--23789
HLA-DPA1--23799
TAPBPL--23948
CD74--24030
IFI30--24060
HLA-DMB--24219
CANX--24340
RPS27A--24381
UBA52--24384
TAP2--124544
HFE0.25124705
HLA-DMA--24770
PROCR--24903
MICB--25021
PSMB5--25250
SAR1B--25590
MR1--25760

Network

GO:0019882

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
PSMA5proteasome (prosome, macropain) subunit, alpha type, 5 Entrez:5686  Ensembl: ENSG00000143106  HGNC: 9534  HPRD: 01464 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA5proteasome (prosome, macropain) subunit, alpha type, 5
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA5PSMA5proteasome (prosome, macropain) subunit, alpha type, 5

Troyanskaya Laboratory - Princeton University