ASD

GO:0017157 regulation of exocytosis (59)

GeneInput weightStandardRank
SYT1--11
VAMP2--33
PLCB1--148
CADPS--133
ABR--160
CACNA1A--1270
STX1A0.251512
PFN2--551
CRHR1--589
SNCA--1667
STXBP1--769
IL1RAPL10.251774
RAB3A0.251848
RAPGEF40.251904
DOC2A0.2511359
ADRA2A0.2511399
SYT7--1536
BCR--11839
RAB3B--1982
SEPT5--2143
RAB26--2496
NCS1--2628
SCAMP50.2512682
NOTCH1--12865
GLRA1--2965
CDK50.2513194
GAB2--3496
FOXF1--13518
STXBP5--3733
CACNA1H1.013855
STX1B--3973
RALA--4169
RAB3C--4397
LGI3--4664
SYT9--5512
RALB--5931
NAPB--6293
TRPV6--7927
RPH3AL--8235
STXBP2--18948
NSF--9493
REST--9779
DOC2B--11084
RAB27B--12713
MS4A2--13136
FGF2--13150
RSG1--14486
ZP4--14747
ZP3--17443
F2RL1--19969
UNC13D--121158
RAB3D--21252
FCER1G--21507
B4GALT1--122700
PLD2--22908
CCR2--23296
SYK--23906
HMOX1--23938
STXBP3--25176

Network

GO:0017157

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CADPSCa++-dependent secretion activator Entrez:8618  Ensembl: ENSG00000163618  HGNC: 1426  HPRD: 05236 
ABRactive BCR-related Entrez:29  HGNC: 81  HPRD: 02649  Ensembl: ENSG00000159842 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCa++-dependent secretion activator
ABRactive BCR-related
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCADPSCa++-dependent secretion activator
ABRABRactive BCR-related

Troyanskaya Laboratory - Princeton University