GO:0008207 C21-steroid hormone metabolic process (28)

GeneInput weightStandardRank
NR3C1--496
CRH--563
YWHAH--2009
STAT5B--2593
CYP19A10.2513823
CACNA1H1.013855
CYP17A10.2513984
HSD3B2--4818
SRD5A10.2514966
AKR1D1--15546
HSD3B1--5560
CYP11B10.2516613
CYP11A10.2518063
STAR--8811
HSD11B10.2518910
HSD11B2--9892
DHRS2--11471
AFP--11538
SERPINA6--12381
FSHB0.25112923
FGF2--13150
CYP21A20.25113362
CYP11B2--13660
DHRS9--18976
LHB0.25119520
ADM--21106
STARD5--22138
AKR1B1--22159

Network

GO:0008207

Network
Enrichment
NameDescriptionExternal IDs
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
CRHcorticotropin releasing hormone Entrez:1392  Ensembl: ENSG00000147571  HPRD: 07172  HGNC: 2355 
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide Entrez:7533  HGNC: 12853  Ensembl: ENSG00000128245  HPRD: 00215 
STAT5Bsignal transducer and activator of transcription 5B Entrez:6777  HGNC: 11367  Ensembl: ENSG00000173757  HPRD: 05037 
CYP19A1cytochrome P450, family 19, subfamily A, polypeptide 1 Entrez:1588  HGNC: 2594  Ensembl: ENSG00000137869  HPRD: 00488 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
CRHcorticotropin releasing hormone
YWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
STAT5Bsignal transducer and activator of transcription 5B
CYP19A1cytochrome P450, family 19, subfamily A, polypeptide 1
Query geneGeneGene descriptionEdge score
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
CRHCRHcorticotropin releasing hormone
YWHAHYWHAHtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
STAT5BSTAT5Bsignal transducer and activator of transcription 5B
CYP19A1CYP19A1cytochrome P450, family 19, subfamily A, polypeptide 1