ASD

GO:0032006 regulation of TOR signaling cascade (24)

GeneInput weightStandardRank
RICTOR--537
TSC10.251790
SLC7A1--2961
DDIT4--3443
RHEB--3728
UBR2--4054
GSK3A--4141
RRAGA--4695
MLST8--5028
UBR1--15553
RRAGB--6607
RRAGC--7372
SLC7A3--7473
GOLPH3--8151
LAMTOR2--8770
RRAGD--9082
TSC20.2519351
AGPAT9--10292
DEPTOR--10635
AKT1S1--13569
RPTOR--14284
LAMTOR3--20937
LAMTOR1--22090
TMEM127--22217

Network

GO:0032006

Network
Enrichment
NameDescriptionExternal IDs
RICTORRPTOR independent companion of MTOR, complex 2 Entrez:253260  HGNC: 28611  HPRD: 10682  Ensembl: ENSG00000164327 
TSC1tuberous sclerosis 1 Entrez:7248  Ensembl: ENSG00000165699  HGNC: 12362  HPRD: 05594 
SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 Entrez:6541  HGNC: 11057  HPRD: 00091  Ensembl: ENSG00000139514 
DDIT4DNA-damage-inducible transcript 4 Entrez:54541  HGNC: 24944  Ensembl: ENSG00000168209  HPRD: 09662 
RHEBRas homolog enriched in brain Entrez:6009  HGNC: 10011  HPRD: 03188  Ensembl: ENSG00000106615 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RICTORRPTOR independent companion of MTOR, complex 2
TSC1tuberous sclerosis 1
SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
DDIT4DNA-damage-inducible transcript 4
RHEBRas homolog enriched in brain
Query geneGeneGene descriptionEdge score
RICTORRICTORRPTOR independent companion of MTOR, complex 2
TSC1TSC1tuberous sclerosis 1
SLC7A1SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
DDIT4DDIT4DNA-damage-inducible transcript 4
RHEBRHEBRas homolog enriched in brain

Troyanskaya Laboratory - Princeton University