ASD

GO:0045739 positive regulation of DNA repair (22)

GeneInput weightStandardRank
UBE2N--734
EYA1--11141
SIRT1--1233
PRKCG--11483
UBE2V2--1939
FGF10--14532
CEBPG--4660
UIMC1--6729
RNF8--7620
H2AFX--8720
BABAM1--9983
EYA3--11065
PARG--11629
RNF168--13760
BRE--19475
APEX1--20571
ERCC8--120608
BRCC3--20674
FAM175A--22994
MGMT--24063
BRCA1--124573
TMEM161A--24630

Network

GO:0045739

Network
Enrichment
NameDescriptionExternal IDs
UBE2Nubiquitin-conjugating enzyme E2N Entrez:7334  HGNC: 12492  HPRD: 04725 
EYA1eyes absent homolog 1 (Drosophila) Entrez:2138  Ensembl: ENSG00000104313  HGNC: 3519  HPRD: 03388 
SIRT1sirtuin 1 Entrez:23411  Ensembl: ENSG00000096717  HPRD: 08381  HGNC: 14929 
PRKCGprotein kinase C, gamma Entrez:5582  HGNC: 9402  HPRD: 01502  Ensembl: ENSG00000126583 
UBE2V2ubiquitin-conjugating enzyme E2 variant 2 Entrez:7336  HPRD: 04300  HGNC: 12495 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
UBE2Nubiquitin-conjugating enzyme E2N
EYA1eyes absent homolog 1 (Drosophila)
SIRT1sirtuin 1
PRKCGprotein kinase C, gamma
UBE2V2ubiquitin-conjugating enzyme E2 variant 2
Query geneGeneGene descriptionEdge score
UBE2NUBE2Nubiquitin-conjugating enzyme E2N
EYA1EYA1eyes absent homolog 1 (Drosophila)
SIRT1SIRT1sirtuin 1
PRKCGPRKCGprotein kinase C, gamma
UBE2V2UBE2V2ubiquitin-conjugating enzyme E2 variant 2

Troyanskaya Laboratory - Princeton University