ASD

GO:0050690 regulation of defense response to virus by virus (28)

GeneInput weightStandardRank
AP2S1--210
AP2M1--779
FYN--932
ARF1--1225
RAC1--1617
AP1G1--1643
ELMO1--1914
AP2A2--2352
PAK2--4270
AP2A1--4845
AP1S2--4868
ATP6V1H--5369
AP1S1--6741
AP2B1--6850
CD28--6931
CD4--9401
PACS1--10868
AP1S3--12137
AP1M1--19590
HLA-A0.25119612
CD8B--19980
CD247--21414
AP1B1--21783
B2M--22154
HCK--22517
AP1M2--23440
DOCK2--23744
LCK--24753

Network

GO:0050690

Network
Enrichment
NameDescriptionExternal IDs
AP2S1adaptor-related protein complex 2, sigma 1 subunit Entrez:1175  HPRD: 03762  Ensembl: ENSG00000042753  HGNC: 565 
AP2M1adaptor-related protein complex 2, mu 1 subunit Entrez:1173  Ensembl: ENSG00000161203  HPRD: 03014  HGNC: 564 
FYNFYN oncogene related to SRC, FGR, YES Entrez:2534  HGNC: 4037  Ensembl: ENSG00000010810  HPRD: 00655 
ARF1ADP-ribosylation factor 1 Entrez:375  Ensembl: ENSG00000143761  HGNC: 652  HPRD: 00054 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
AP2S1adaptor-related protein complex 2, sigma 1 subunit
AP2M1adaptor-related protein complex 2, mu 1 subunit
FYNFYN oncogene related to SRC, FGR, YES
ARF1ADP-ribosylation factor 1
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Query geneGeneGene descriptionEdge score
AP2S1AP2S1adaptor-related protein complex 2, sigma 1 subunit
AP2M1AP2M1adaptor-related protein complex 2, mu 1 subunit
FYNFYNFYN oncogene related to SRC, FGR, YES
ARF1ARF1ADP-ribosylation factor 1
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

Troyanskaya Laboratory - Princeton University