ASD

GO:0050665 hydrogen peroxide biosynthetic process (6)

GeneInput weightStandardRank
SOD1--12702
CYP1A10.2515067
CYP1A2--6074
DUOX1--7090
CYBA--17322
SOD2--22687

Network

GO:0050665

Network
Enrichment
NameDescriptionExternal IDs
SOD1superoxide dismutase 1, soluble Entrez:6647  HGNC: 11179  Ensembl: ENSG00000142168  HPRD: 00937 
CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 1 Entrez:1543  HGNC: 2595  HPRD: 00148  Ensembl: ENSG00000140465 
CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2 Entrez:1544  HPRD: 00489  HGNC: 2596  Ensembl: ENSG00000140505 
DUOX1dual oxidase 1 Entrez:53905  HGNC: 3062  Ensembl: ENSG00000137857  HPRD: 08421 
CYBAcytochrome b-245, alpha polypeptide Entrez:1535  HGNC: 2577  Ensembl: ENSG00000051523  HPRD: 01989 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOD1superoxide dismutase 1, soluble
CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2
DUOX1dual oxidase 1
CYBAcytochrome b-245, alpha polypeptide
Query geneGeneGene descriptionEdge score
SOD1SOD1superoxide dismutase 1, soluble
CYP1A1CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 2
DUOX1DUOX1dual oxidase 1
CYBACYBAcytochrome b-245, alpha polypeptide

Troyanskaya Laboratory - Princeton University