ASD

GO:0010907 positive regulation of glucose metabolic process (23)

GeneInput weightStandardRank
AKT10.2511020
HIF1A--1075
DYRK2--1203
IRS2--11300
IRS1--11374
ARPP19--1601
PPARGC1A--1909
GCK--12660
IGF10.2512793
AKT2--13912
ADRA1B0.2514946
INSR--15872
STK11--16000
SORBS1--6411
PTH--6947
PMAIP1--7385
GAPDHS--8787
C1QTNF2--10034
MLXIPL--11075
INS--122047
IGF20.25122401
HNF4A--122965
ARNT--23123

Network

GO:0010907

Network
Enrichment
NameDescriptionExternal IDs
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 Entrez:8445  HGNC: 3093  HPRD: 04606 
IRS2insulin receptor substrate 2 Entrez:8660  HPRD: 02878  HGNC: 6126  Ensembl: ENSG00000185950 
IRS1insulin receptor substrate 1 Entrez:3667  HPRD: 00943  HGNC: 6125 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
AKT1v-akt murine thymoma viral oncogene homolog 1
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
IRS2insulin receptor substrate 2
IRS1insulin receptor substrate 1
Query geneGeneGene descriptionEdge score
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
DYRK2DYRK2dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
IRS2IRS2insulin receptor substrate 2
IRS1IRS1insulin receptor substrate 1

Troyanskaya Laboratory - Princeton University