ASD

GO:0051940 regulation of catecholamine uptake involved in synaptic transmission (6)

GeneInput weightStandardRank
SNCA--1667
DRD10.251899
DRD20.2513749
DRD30.2514349
GDNF--14658
DRD40.2517021

Network

GO:0051940

Network
Enrichment
NameDescriptionExternal IDs
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
DRD2dopamine receptor D2 Entrez:1813  HPRD: 00539  Ensembl: ENSG00000149295  HGNC: 3023 
DRD3dopamine receptor D3 Entrez:1814  HGNC: 3024  Ensembl: ENSG00000151577  HPRD: 00540 
GDNFglial cell derived neurotrophic factor Entrez:2668  HGNC: 4232  Ensembl: ENSG00000168621  HPRD: 02906 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
DRD1dopamine receptor D1
DRD2dopamine receptor D2
DRD3dopamine receptor D3
GDNFglial cell derived neurotrophic factor
Query geneGeneGene descriptionEdge score
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
DRD1DRD1dopamine receptor D1
DRD2DRD2dopamine receptor D2
DRD3DRD3dopamine receptor D3
GDNFGDNFglial cell derived neurotrophic factor

Troyanskaya Laboratory - Princeton University