ASD

GO:0080135 regulation of cellular response to stress (181)

GeneInput weightStandardRank
NTRK30.2516
PLCB1--148
GRIK20.51232
RAP2A--324
MAPK8IP2--418
MAP3K9--462
SPAG9--558
MAP4K4--565
MAPK8IP1--1605
UBE2N--734
OMG0.251808
TGFB2--834
USP1--917
NCOR1--1019
AKT10.2511020
HIPK2--1051
NDEL10.2511074
BMP7--1137
CDC42--1138
EYA1--11141
COPS5--1158
GAB1--1198
MAP3K5--1220
SIRT1--1233
MAP3K7--1275
SEMA4C--1304
TAOK1--1336
FZD7--1357
PRKCG--11483
PPP4C0.2511534
MIF0.2511552
TAOK20.2511633
UBE2V2--1939
PKN1--1967
XYLT1--12057
DVL3--2090
MID1--2259
MAPK8IP3--2274
TERF2IP--2298
PSMD10--2412
PDCD4--2707
RTN4--2735
MAP4K5--2894
ITCH--2932
FZD10--2957
MAP3K10--2968
PTK2B--3063
MSX1--13127
MAP3K2--3184
WNT5A--3319
MAP3K1--13381
TAOK3--3466
DAB2IP--3482
ATM--13622
MAP3K4--3663
DIXDC1--3734
TNR--3868
AKT2--13912
FOXO10.2513947
WNT16--4117
AXIN2--14260
WNT1--4383
AXIN1--14419
FGF10--14532
TRAF4--4556
IL1A--4651
CEBPG--4660
MEN1--14917
PAK1--4940
EDA2R--4972
MECOM--4979
CBS0.2515018
DUSP10--5172
FEM1B--5206
TNFRSF11A--15293
MAP2K7--5837
DUSP19--6060
ZEB2--6361
DVL2--6546
MDM2--6675
UIMC1--6729
TWIST1--16980
WNT7B--7113
SFRP4--7310
WNT7A--7312
PMAIP1--7385
PPP4R2--7398
FGD4--17457
PPEF2--7509
RNF8--7620
NFE2L2--7853
HIPK3--8282
DUSP3--8506
DAXX--8508
H2AFX--8720
GSTP10.2518742
SNAI1--9198
SMYD2--9412
EDN1--9540
SCARF1--9851
BABAM1--9983
LYN--10336
CLN3--110442
IL1B--110818
TLR6--10981
UBE2V1--11027
TRAF6--11055
EYA3--11065
PARG--11629
IL26--11645
ZNF675--11676
FGF19--12130
KDM1A--12183
SPP1--12442
SH3RF1--12767
MAP3K11--12938
TLR9--13360
MDFI--13519
RNF168--13760
CCL19--14578
SETD8--14849
POLH--115096
TNF0.25115243
HP--17916
GPS2--17956
TP73--18810
BRE--19475
BIRC7--19826
SDCBP--19967
F2RL1--19969
AMBP--20003
PTPLAD1--20272
FKTN--120500
MAP4K2--20522
APEX1--20571
CDKN2A--120587
ERCC8--120608
TIRAP--20658
BRCC3--20674
CD44--20701
RIPK2--20830
MTOR--21095
BECN1--21459
NOD2--121514
MDFIC--21692
HDAC3--21702
CCL21--21829
MAP4K1--22336
CCR7--22367
DBNL--22402
NBR1--22425
TLR3--22478
TPD52L1--22519
KLK8--22593
RIPK1--22681
CD27--22836
MUL1--22953
FAM175A--22994
MYD88--23106
NOD1--23388
CARD9--123577
CD36--23662
TRAF2--23686
FBLN5--123689
ATR--123866
SYK--23906
SNAI2--123962
CD74--24030
MGMT--24063
MAP3K6--24220
RTEL1--24350
BRCA1--124573
TMEM161A--24630
DUSP22--24825
RPA2--24984
IGBP1--25127
EEF1E1--25145
AIDA--25211
IL1RN0.25125385
RPS3--25585
FOXM1--25656

Network

GO:0080135

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
RAP2ARAP2A, member of RAS oncogene family Entrez:5911  HGNC: 9861  HPRD: 01547 
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
GRIK2glutamate receptor, ionotropic, kainate 2
RAP2ARAP2A, member of RAS oncogene family
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
RAP2ARAP2ARAP2A, member of RAS oncogene family
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2

Troyanskaya Laboratory - Princeton University