ASD

GO:0046068 cGMP metabolic process (21)

GeneInput weightStandardRank
ATP2B20.513
HTR2C0.25162
GUCY1B3--873
PDE2A--1938
GUCY1A3--1997
GUCY1A2--2093
PDE1B--2534
PDE11A--2780
RORA--3270
GUCY2F--5264
PDE5A--5684
HTR2B--6992
NPR2--17127
NPPB--7334
GUCY2D--17484
NPPA--19231
NPPC--9349
GUCA2B--10165
GUCY2C--10523
AQP1--22433
NPR1--24948

Network

GO:0046068

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Entrez:3358  HGNC: 5295  HPRD: 02429  Ensembl: ENSG00000147246 
GUCY1B3guanylate cyclase 1, soluble, beta 3 Entrez:2983  HGNC: 4687  Ensembl: ENSG00000061918  HPRD: 00769 
PDE2Aphosphodiesterase 2A, cGMP-stimulated Entrez:5138  HGNC: 8777  Ensembl: ENSG00000186642  HPRD: 04041 
GUCY1A3guanylate cyclase 1, soluble, alpha 3 Entrez:2982  HGNC: 4685  HPRD: 00768  Ensembl: ENSG00000164116 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
HTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GUCY1B3guanylate cyclase 1, soluble, beta 3
PDE2Aphosphodiesterase 2A, cGMP-stimulated
GUCY1A3guanylate cyclase 1, soluble, alpha 3
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
HTR2CHTR2C5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
GUCY1B3GUCY1B3guanylate cyclase 1, soluble, beta 3
PDE2APDE2Aphosphodiesterase 2A, cGMP-stimulated
GUCY1A3GUCY1A3guanylate cyclase 1, soluble, alpha 3

Troyanskaya Laboratory - Princeton University