ASD

GO:0032956 regulation of actin cytoskeleton organization (131)

GeneInput weightStandardRank
EP300--1318
SFRP1--387
RICTOR--537
PFN1--548
PFN2--551
CDK5R1--586
SLIT2--659
TAC10.251726
NEBL--731
TSC10.251790
ACTR3--803
SMAD3--823
ARPC1A--901
SHROOM2--937
PARK20.251952
PROX1--997
KANK1--1150
DLC1--1282
SPTAN1--11287
AMOT--1325
BAIAP20.2511353
DMTN--1465
RAC1--1617
SPTBN4--1647
ARPC2--1648
VANGL2--1793
ARPC5L--1833
SPTBN2--11935
RASA1--1983
TMSB10--2139
SSH2--2172
CAPZB--2179
RHOA--2292
ADD2--2388
ARPC5--2454
LATS1--2781
ADD1--12876
ARPC4--2880
TMSB15A--2947
FZD10--2957
NCK2--3077
TMSB15B--3139
ARF6--3317
MAP3K1--13381
SPTB--3478
CCDC88A--3536
SPTBN1--3627
PDGFA--3731
DIXDC1--3734
ACTR3B--3786
NEB--3801
DLG1--3822
SSH1--4066
LIMK1--4265
S1PR1--4301
CAPZA2--4483
JAM3--4580
RDX--14697
PAK1--4940
CAPZA1--4983
MLST8--5028
SPTBN5--5319
ARHGAP6--5374
ARPC1B--5545
JMY--5725
NF2--15991
CELSR1--6180
TMSB4X--6302
DSTN--6316
ARPC3--6500
SPTA1--16958
ARHGEF10--7111
ILK--7305
GRHL3--7409
CXCL12--7802
WNT11--7820
AVIL--7943
CAPZA3--8396
KISS1R--9434
EDN1--9540
CCL11--9615
SCIN--9620
CDC42EP5--9805
WASH3P--10817
WASH2P--11022
TWF1--11060
TACR1--11618
RHOC--11655
MYLK3--12362
SORBS3--12437
PDXP--12453
NCK1--12890
TMSB4Y--13524
WASH6P--13829
TMSB4XP8--14081
RHOQ--14092
ARHGEF19--14560
PRKCQ--15381
CAV3--115414
WASH1--15718
TMSB4XP4--17717
WASH4P--17760
ARHGEF10L--17881
CDC42EP2--19500
F2RL1--19969
ACTR3C--20146
CORO1A--20339
CAPG--20663
MTOR--21095
CCL21--21829
CCL24--21868
VIL10.5122243
LRP1--22276
VILL--22283
CCR7--22367
GPR65--22555
CCL26--22814
TWF2--23010
SDC4--23067
PDGFRB--23242
NCKAP1L--23771
SSH3--23947
GSN--124007
BAIAP2L1--24041
TRIOBP--124113
PLEK--24240
TPM1--124247
LIMA1--24553
FHOD1--24802
ARAP1--24899
SYNPO--25125

Network

GO:0032956

Network
Enrichment
NameDescriptionExternal IDs
EP300E1A binding protein p300 Entrez:2033  Ensembl: ENSG00000100393  HGNC: 3373  HPRD: 04078 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
RICTORRPTOR independent companion of MTOR, complex 2 Entrez:253260  HGNC: 28611  HPRD: 10682  Ensembl: ENSG00000164327 
PFN1profilin 1 Entrez:5216  Ensembl: ENSG00000108518  HGNC: 8881  HPRD: 01452 
PFN2profilin 2 Entrez:5217  Ensembl: ENSG00000070087  HGNC: 8882  HPRD: 01451 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
EP300E1A binding protein p300
SFRP1secreted frizzled-related protein 1
RICTORRPTOR independent companion of MTOR, complex 2
PFN1profilin 1
PFN2profilin 2
Query geneGeneGene descriptionEdge score
EP300EP300E1A binding protein p300
SFRP1SFRP1secreted frizzled-related protein 1
RICTORRICTORRPTOR independent companion of MTOR, complex 2
PFN1PFN1profilin 1
PFN2PFN2profilin 2

Troyanskaya Laboratory - Princeton University