ASD

GO:0070167 regulation of biomineral tissue development (49)

GeneInput weightStandardRank
BMPR2--1281
DICER1--1762
SMAD3--823
ACVR2A--965
SOX9--1970
BMP7--1137
BMPR1A--1140
WNT10B--1517
ACVR2B--11676
FBN2--2131
BCOR--12290
BMPR1B--12316
TFAP2A--12923
AMELX--13396
ANKH--3475
FGF23--13888
KL--3938
BMP6--4358
STATH--4554
BMP2--14855
WNT6--5106
OSR1--5691
ACVR1--16054
ENPP1--16091
MMP20--16407
BMP4--16499
TWIST1--16980
P2RX7--7888
PKDCC--9871
AHSG--11515
ASPN--11718
DDR2--12143
TGFB3--113097
CD276--13688
BMP2K--14273
IFITM5--14395
PPARGC1B--115356
PHOSPHO1--15802
TGFB10.25120135
BGLAP--20875
OSR2--20931
SRGN--21336
CYP27B1--21369
WNT4--21809
NBR1--22425
PLA2G4A--22727
ADRB20.25123251
MGP--23957
ECM1--124768

Network

GO:0070167

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
DICER1dicer 1, ribonuclease type III Entrez:23405  HGNC: 17098  Ensembl: ENSG00000100697  HPRD: 05875 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
ACVR2Aactivin A receptor, type IIA Entrez:92  HGNC: 173  HPRD: 00025  Ensembl: ENSG00000121989 
SOX9SRY (sex determining region Y)-box 9 Entrez:6662  HPRD: 06427  HGNC: 11204  Ensembl: ENSG00000125398 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
DICER1dicer 1, ribonuclease type III
SMAD3SMAD family member 3
ACVR2Aactivin A receptor, type IIA
SOX9SRY (sex determining region Y)-box 9
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
DICER1DICER1dicer 1, ribonuclease type III
SMAD3SMAD3SMAD family member 3
ACVR2AACVR2Aactivin A receptor, type IIA
SOX9SOX9SRY (sex determining region Y)-box 9

Troyanskaya Laboratory - Princeton University