ASD

GO:2000273 positive regulation of receptor activity (12)

GeneInput weightStandardRank
FBXW7--198
ADORA1--960
ADRA2A0.2511399
TGFA--1873
ADAM17--5323
ADRA2C--8551
EREG--9052
ADRA2B--10119
EPGN--12503
EGF0.25112881
PPARGC1B--115356
IGF20.25122401

Network

GO:2000273

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
TGFAtransforming growth factor, alpha Entrez:7039  HPRD: 07522  HGNC: 11765  Ensembl: ENSG00000163235 
ADAM17ADAM metallopeptidase domain 17 Entrez:6868  Ensembl: ENSG00000151694  HPRD: 04703  HGNC: 195 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ADORA1adenosine A1 receptor
ADRA2Aadrenoceptor alpha 2A
TGFAtransforming growth factor, alpha
ADAM17ADAM metallopeptidase domain 17
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ADORA1ADORA1adenosine A1 receptor
ADRA2AADRA2Aadrenoceptor alpha 2A
TGFATGFAtransforming growth factor, alpha
ADAM17ADAM17ADAM metallopeptidase domain 17

Troyanskaya Laboratory - Princeton University