ASD

GO:0016055 Wnt receptor signaling pathway (150)

GeneInput weightStandardRank
USP34--231
SOX4--250
APC0.251266
LRP6--279
SFRP1--387
CELSR2--410
GSK3B--427
TLE4--497
CDK140.251536
TBL1XR10.251581
MARK4--603
CSNK1A1--682
CSNK1D--699
FBXW11--859
CUL31.011093
APC2--1115
CSNK2B--1126
CDC42--1138
TBL1X0.2511228
AES--1230
FZD7--1357
CSNK1G2--1365
PTEN1.011389
TNKS--1414
NDP--11484
CHD81.011493
LEF1--1499
WNT10B--1517
TNIK--1531
RAC1--1617
CSNK1G1--1655
WNT2B--1673
RAB5A--1688
VANGL2--1793
WIF1--1882
BTRC--1884
RNF138--2037
PPM1A--2070
BCL9--2079
DVL3--2090
MCC--2167
STRN--2195
FZD4--12229
WNT20.2512299
GATA3--2376
PTPRU--2673
BRD7--2901
FZD8--2933
CTNND1--2948
FZD10--2957
SOSTDC1--3003
FZD3--3193
CSNK1G3--3255
WNT5A--3319
HBP1--3343
RSPO3--3347
TLE3--3389
WNT8B--3407
TCF7L20.513548
DRD20.2513749
PIAS4--3989
PYGO1--4013
UBE2B--4057
WNT16--4117
AXIN2--14260
DACT1--4304
WNT1--4383
TNKS2--4385
AXIN1--14419
WNT3--4613
CYLD--14624
RSPO2--4631
WISP1--4689
DRAXIN--4717
WNT3A--4747
WNT6--5106
CSNK1A1L--5166
RYK--5383
ARL6--15581
CSNK2A1--5948
STK11--16000
FZD9--6246
PORCN--16248
MITF--16345
TLE2--6532
DVL2--6546
SOST--6885
WNT7B--7113
SFRP4--7310
WNT7A--7312
GRHL3--7409
NKD1--7670
WNT8A--7814
WNT11--7820
RNF146--7910
RSPO4--18097
CD24--18102
WNT9B--8217
RARG0.2518575
WNT10A--8604
TCF7--8813
CTNNB10.519066
LRP5--19420
HOXB9--9713
SMO0.25110504
PPAP2B--10628
NKD2--10641
CCNY--10662
LDB1--10693
KREMEN1--10806
PYGO2--11014
SFRP5--11273
LZTS20.25111412
CALCOCO1--11527
CSNK2A2--11717
ZBTB33--12774
KREMEN2--13170
FRAT1--13218
AMER1--13306
WNT9A--13365
FRAT2--13390
NPHP3--113474
PTK7--13643
LRRFIP2--14565
INVS--114708
WNT5B--15534
WLS--15707
FZD2--16930
CCDC88C--18057
FBXW4--18142
DVL1P1--18731
DVL1--18924
DDB1--19185
FZD6--19921
JUP--120291
CPZ--20659
CD44--20701
FZD1--20775
KLHL12--21359
WNT4--21809
SLC9A3R1--21898
LRP5L--22282
SDC1--22626
NXN--22883
FZD5--23249
MESDC2--23416
TGFB1I1--23709
SNAI2--123962
CCNE1--24359
CAV1--125381

Network

GO:0016055

Network
Enrichment
NameDescriptionExternal IDs
USP34ubiquitin specific peptidase 34 Entrez:9736  HGNC: 20066  HPRD: 11665  Ensembl: ENSG00000115464 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
USP34ubiquitin specific peptidase 34
SOX4SRY (sex determining region Y)-box 4
APCadenomatous polyposis coli
LRP6low density lipoprotein receptor-related protein 6
SFRP1secreted frizzled-related protein 1
Query geneGeneGene descriptionEdge score
USP34USP34ubiquitin specific peptidase 34
SOX4SOX4SRY (sex determining region Y)-box 4
APCAPCadenomatous polyposis coli
LRP6LRP6low density lipoprotein receptor-related protein 6
SFRP1SFRP1secreted frizzled-related protein 1

Troyanskaya Laboratory - Princeton University