ASD

GO:0042308 negative regulation of protein import into nucleus (34)

GeneInput weightStandardRank
NF10.251372
G3BP2--610
FBXW11--859
APC2--1115
PKIA--1118
BMP7--1137
MXI1--11763
PSMD10--2412
DAB2IP--3482
AKAP1--4078
AXIN2--14260
MAPK7--4384
CYLD--14624
NLRP30.2514959
NFKBIA--5569
KEAP1--6103
IL10--19513
SFRP5--11273
UACA--12955
MDFI--13519
NFKBIE--19710
EMD--120034
NFKBIL1--20431
TONSL--20639
FZD1--20775
MTOR--21095
TACC3--21671
MDFIC--21692
PKIG--22117
NFKBIB--22875
FAF1--23304
CD36--23662
SNAI2--123962
WWTR1--24317

Network

GO:0042308

Network
Enrichment
NameDescriptionExternal IDs
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
G3BP2GTPase activating protein (SH3 domain) binding protein 2 Entrez:9908  HPRD: 06570  HGNC: 30291  Ensembl: ENSG00000138757 
FBXW11F-box and WD repeat domain containing 11 Entrez:23291  Ensembl: ENSG00000072803  HPRD: 07294  HGNC: 13607 
APC2adenomatosis polyposis coli 2 Entrez:10297  Ensembl: ENSG00000115266  HGNC: 24036  HPRD: 09802 
PKIAprotein kinase (cAMP-dependent, catalytic) inhibitor alpha Entrez:5569  HGNC: 9017  Ensembl: ENSG00000171033  HPRD: 05828 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NF1neurofibromin 1
G3BP2GTPase activating protein (SH3 domain) binding protein 2
FBXW11F-box and WD repeat domain containing 11
APC2adenomatosis polyposis coli 2
PKIAprotein kinase (cAMP-dependent, catalytic) inhibitor alpha
Query geneGeneGene descriptionEdge score
NF1NF1neurofibromin 1
G3BP2G3BP2GTPase activating protein (SH3 domain) binding protein 2
FBXW11FBXW11F-box and WD repeat domain containing 11
APC2APC2adenomatosis polyposis coli 2
PKIAPKIAprotein kinase (cAMP-dependent, catalytic) inhibitor alpha

Troyanskaya Laboratory - Princeton University