ASD

GO:0042475 odontogenesis of dentine-containing tooth (44)

GeneInput weightStandardRank
LRP6--279
PDGFRA--1320
EDA--1925
BCL11B--1125
BMP7--1137
BMPR1A--1140
HDAC2--1440
LEF1--1499
LRP4--1500
ACVR2B--11676
BSG--1821
DLX20.2512357
DLX10.2512400
SOSTDC1--3003
MSX1--13127
AMBN--3337
AMELX--13396
BCL2L11--3469
LHX8--3904
FGF10--14532
FGF4--4938
WNT6--5106
ODAM--5531
NF2--15991
GLI3--16261
BMP4--16499
NKX2-3--6924
WNT7B--7113
LAMA5--7171
GLI2--17307
CTNNB10.519066
CTNNA1--9331
SMO0.25110504
EDAR--110537
GATA6--110828
AMTN--12142
HDAC1--12825
FOXC1--113793
FST--14783
SHH--118571
ADM--21106
CA2--121392
ITGA6--22166
TP63--122528

Network

GO:0042475

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
EDAectodysplasin A Entrez:1896  HPRD: 02347  Ensembl: ENSG00000158813  HGNC: 3157 
BCL11BB-cell CLL/lymphoma 11B (zinc finger protein) Entrez:64919  HGNC: 13222  Ensembl: ENSG00000127152  HPRD: 05950 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
EDAectodysplasin A
BCL11BB-cell CLL/lymphoma 11B (zinc finger protein)
BMP7bone morphogenetic protein 7
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
EDAEDAectodysplasin A
BCL11BBCL11BB-cell CLL/lymphoma 11B (zinc finger protein)
BMP7BMP7bone morphogenetic protein 7

Troyanskaya Laboratory - Princeton University