ASD

GO:0042306 regulation of protein import into nucleus (96)

GeneInput weightStandardRank
GNAQ--189
UBR5--193
EP300--1318
NF10.251372
G3BP2--610
SMAD4--821
SMAD3--823
FBXW11--859
EDA--1925
ZIC1--939
APC2--1115
PKIA--1118
BMP7--1137
BMPR1A--1140
SIRT1--1233
FZD7--1357
TXN--1408
AKAP5--1759
MXI1--11763
RHOA--2292
PSMD10--2412
EGFR--12546
DAB2IP--3482
IL12B--3596
AKAP1--4078
AXIN2--14260
FLNA--14285
MAPK7--4384
AXIN1--14419
CYLD--14624
WNT3A--4747
NLRP30.2514959
SFRP2--5252
NFKBIA--5569
KEAP1--6103
GLI3--16261
BMP4--16499
TGFBR1--17268
CDKN1A--7714
LACRT--7733
BCL3--7998
BAMBI--8550
IL10--19513
EDAR--110537
IL1B--110818
IL23A--11134
SFRP5--11273
MBTPS1--11794
LEP0.25111864
IL6--112695
TLR4--112795
EGF0.25112881
UACA--12955
TGFB3--113097
TLR9--13360
TLR7--13389
MDFI--13519
CCL19--14578
RBPMS--14967
TNF0.25115243
PRKCQ--15381
SHH--118571
TLR2--119246
POU5F1--19704
NFKBIE--19710
NLRP12--19807
EMD--120034
TGFB10.25120135
JUP--120291
NFKBIL1--20431
TONSL--20639
FZD1--20775
TRIP6--21037
MTOR--21095
TACC3--21671
MDFIC--21692
PKIG--22117
TNFSF14--22260
TLR3--22478
DDX58--22544
RBCK1--22556
CD27--22836
TNFRSF1A--22842
NFKBIB--22875
HNF4A--122965
FAF1--23304
MAVS--23348
CDH1--123589
CD36--23662
SNAI2--123962
SPHK1--24069
WWTR1--24317
TMEM173--24599
OGG1--124604
CDK1--25053
NOLC1--25515

Network

GO:0042306

Network
Enrichment
NameDescriptionExternal IDs
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
UBR5ubiquitin protein ligase E3 component n-recognin 5 Entrez:51366  HPRD: 06436  Ensembl: ENSG00000104517  HGNC: 16806 
EP300E1A binding protein p300 Entrez:2033  Ensembl: ENSG00000100393  HGNC: 3373  HPRD: 04078 
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
G3BP2GTPase activating protein (SH3 domain) binding protein 2 Entrez:9908  HPRD: 06570  HGNC: 30291  Ensembl: ENSG00000138757 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAQguanine nucleotide binding protein (G protein), q polypeptide
UBR5ubiquitin protein ligase E3 component n-recognin 5
EP300E1A binding protein p300
NF1neurofibromin 1
G3BP2GTPase activating protein (SH3 domain) binding protein 2
Query geneGeneGene descriptionEdge score
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
UBR5UBR5ubiquitin protein ligase E3 component n-recognin 5
EP300EP300E1A binding protein p300
NF1NF1neurofibromin 1
G3BP2G3BP2GTPase activating protein (SH3 domain) binding protein 2

Troyanskaya Laboratory - Princeton University