ASD

GO:0008624 induction of apoptosis by extracellular signals (119)

GeneInput weightStandardRank
CAMK2B0.25155
KALRN--56
TRIO0.51111
ABR--160
ARHGEF7--215
ARHGEF4--265
TIAM1--325
RASGRF1--335
ARHGEF12--1393
CRH--563
ARHGEF11--705
SOS1--1810
ARHGEF9--1875
MCF2--892
ADORA1--960
YWHAE--995
PRKCA--1027
MCF2L--1059
SST--1139
SOS2--1181
FGD1--11182
MAPK8--1214
MAP3K5--1220
BAD--1290
RAC1--1617
AKAP13--1679
ITSN1--1789
ARHGEF2--1819
DAPK1--1848
SPECC1L--1912
NDUFA13--12204
MAPK9--2237
RASGRF2--2414
PREX1--2760
VAV2--2850
VAV3--2908
TIAM2--3070
ARHGEF17--3189
BCL2L11--3469
DEDD--3535
TNFRSF25--3659
MAGED1--4068
ARHGEF3--4159
ARHGEF18--4257
SENP1--4701
FASLG--15523
NGFR0.2516212
NGF0.2516229
CASP8AP2--6582
CASP30.2516694
UBC--6756
PTH--6947
FGD4--17457
NET1--7500
DAP3--8246
ADORA2A0.2518408
DAXX--8508
FGD3--8790
DAP--8832
NGFRAP1--9211
NGEF--9344
CASP2--9480
CD3E--9680
BAX--9833
PLEKHG2--10476
PLEKHG5--10686
TRAF6--11055
CD5--11220
SPN--12057
DEDD2--12101
PDCD6--12294
APH1A0.5113440
TNFRSF10B--13570
DPF2--13968
SORT1--14441
TNF0.25115243
SSTR3--18309
PSEN1--18523
ARHGEF6--19241
CFLAR--19385
UBB--19448
FGD2--20103
PSENEN--120566
OBSCN--20605
FASTK0.25120797
NCSTN--120988
ARHGEF16--21200
BAK1--21229
ARHGAP4--21362
CD380.25121442
TNFRSF10A--21740
VDR--21837
TICAM1--21880
RIPK3--22030
BTK--122251
BID--22640
RIPK1--22681
TNFRSF1A--22842
PSEN2--23095
AATF--23243
FADD--23261
DIABLO--23456
SQSTM1--123584
TRAF2--23686
IFI27--23825
VAV1--23876
CASP10--123880
SMPD2--24309
ITGB3BP--24372
RPS27A--24381
UBA52--24384
APH1B--24417
CASP8--124587
FAS--124697
ECT2--24758
CRADD--24961
TNFSF10--25200
TRADD--25265
TM2D1--25807

Network

GO:0008624

Network
Enrichment
NameDescriptionExternal IDs
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta Entrez:816  Ensembl: ENSG00000058404  HGNC: 1461  HPRD: 12127 
KALRNkalirin, RhoGEF kinase Entrez:8997  HPRD: 06859  HGNC: 4814  Ensembl: ENSG00000160145 
TRIOtrio Rho guanine nucleotide exchange factor Entrez:7204  Ensembl: ENSG00000038382  HPRD: 03537  HGNC: 12303 
ABRactive BCR-related Entrez:29  HGNC: 81  HPRD: 02649  Ensembl: ENSG00000159842 
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 7 Entrez:8874  Ensembl: ENSG00000102606  HGNC: 15607  HPRD: 05688 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta
KALRNkalirin, RhoGEF kinase
TRIOtrio Rho guanine nucleotide exchange factor
ABRactive BCR-related
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 7
Query geneGeneGene descriptionEdge score
CAMK2BCAMK2Bcalcium/calmodulin-dependent protein kinase II beta
KALRNKALRNkalirin, RhoGEF kinase
TRIOTRIOtrio Rho guanine nucleotide exchange factor
ABRABRactive BCR-related
ARHGEF7ARHGEF7Rho guanine nucleotide exchange factor (GEF) 7

Troyanskaya Laboratory - Princeton University