ASD

GO:0045936 negative regulation of phosphate metabolic process (78)

GeneInput weightStandardRank
ATXN1--15
PPP2CA--20
YWHAB0.251107
LRP6--279
SFRP1--387
JUN--511
SLIT2--659
SMAD3--823
PARK20.251952
PRKCZ--991
YWHAE--995
BMP7--1137
CDKN1B--1162
PPP2R1A--1163
DYNLL1--1191
SMAD7--1192
PTEN1.011389
GRB10--1910
SMAD6--2305
DUSP6--2466
CDKN2D--2582
PPP2R4--2609
CDKN1C--12938
INPP5J--3690
UBE2B--4057
AKAP1--4078
MAS1--4244
INHA--4765
MEN1--14917
SFRP2--5252
PRNP--15418
INSR--15872
NF2--15991
ADIPOQ0.2516032
ENPP1--16091
BMP4--16499
PRKCD--6504
ERRFI1--6649
TWIST1--16980
PPEF2--7509
CDKN1A--7714
IL2--7838
MET1.018002
SOCS1--9583
BDKRB2--10150
PPAP2B--10628
MLXIPL--11075
AHSG--11515
DKK1--11567
IRF1--111641
FAM129A--13686
CDKN2B--14806
PEBP1--15772
RHOH--16137
INHBA--16974
BDKRB1--18217
PSEN1--18523
DVL1P1--18731
CNKSR3--19160
NLRP12--19807
SAMSN1--19930
TGFB10.25120135
PRKRIP1--20422
CDKN2A--120587
IGFBP3--22342
IBTK--22790
HNF4A--122965
PSEN2--23095
INPP5K--24055
CDKN2C--24062
PTPN6--24184
WWTR1--24317
IMPACT--24430
ENG--124746
IGBP1--25127
CCNB1--25174
CAV1--125381
DNAJC10--25717

Network

GO:0045936

Network
Enrichment
NameDescriptionExternal IDs
ATXN1ataxin 1 Entrez:6310  Ensembl: ENSG00000124788  HPRD: 03333  HGNC: 10548 
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATXN1ataxin 1
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
LRP6low density lipoprotein receptor-related protein 6
SFRP1secreted frizzled-related protein 1
Query geneGeneGene descriptionEdge score
ATXN1ATXN1ataxin 1
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
LRP6LRP6low density lipoprotein receptor-related protein 6
SFRP1SFRP1secreted frizzled-related protein 1

Troyanskaya Laboratory - Princeton University