ASD

GO:0002072 optic cup morphogenesis involved in camera-type eye development (6)

GeneInput weightStandardRank
SOX11--96
PAX2--653
TFAP2A--12923
WNT5A--3319
WNT16--4117
ALDH1A3--21739

Network

GO:0002072

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha) Entrez:7020  Ensembl: ENSG00000137203  HGNC: 11742  HPRD: 00128 
WNT5Awingless-type MMTV integration site family, member 5A Entrez:7474  Ensembl: ENSG00000114251  HPRD: 01293  HGNC: 12784 
WNT16wingless-type MMTV integration site family, member 16 Entrez:51384  HGNC: 16267  HPRD: 05882  Ensembl: ENSG00000002745 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
PAX2paired box 2
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
WNT5Awingless-type MMTV integration site family, member 5A
WNT16wingless-type MMTV integration site family, member 16
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
PAX2PAX2paired box 2
TFAP2ATFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
WNT5AWNT5Awingless-type MMTV integration site family, member 5A
WNT16WNT16wingless-type MMTV integration site family, member 16

Troyanskaya Laboratory - Princeton University