ASD

GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process (30)

GeneInput weightStandardRank
SUMO1--1411
TRIB2--472
CSNK1D--699
CSNK1E0.251752
AKT10.2511020
SMAD7--1192
PTEN1.011389
RCHY1--1615
UBE2V2--1939
PSMD10--2412
TRIB1--3431
SUMO2--4064
STUB1--4250
RNF180--4255
PRICKLE1--15552
DNAJB2--6026
MDM2--6675
VCP--7434
LRRK2--18802
HSPBP1--9785
USP5--9852
TAF1--10729
GCLC--12360
PSEN1--18523
NUB1--21779
GNB2L1--23282
FBXO22--23669
DAB2--25338
CLU--25437
PLK1--25783

Network

GO:0032436

Network
Enrichment
NameDescriptionExternal IDs
SUMO1small ubiquitin-like modifier 1 Entrez:7341  Ensembl: ENSG00000116030  HGNC: 12502  HPRD: 03554 
TRIB2tribbles homolog 2 (Drosophila) Entrez:28951  HPRD: 18224  HGNC: 30809  Ensembl: ENSG00000071575 
CSNK1Dcasein kinase 1, delta Entrez:1453  Ensembl: ENSG00000141551  HGNC: 2452  HPRD: 02920 
CSNK1Ecasein kinase 1, epsilon Entrez:1454  HPRD: 02919  Ensembl: ENSG00000213923  HGNC: 2453 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SUMO1small ubiquitin-like modifier 1
TRIB2tribbles homolog 2 (Drosophila)
CSNK1Dcasein kinase 1, delta
CSNK1Ecasein kinase 1, epsilon
AKT1v-akt murine thymoma viral oncogene homolog 1
Query geneGeneGene descriptionEdge score
SUMO1SUMO1small ubiquitin-like modifier 1
TRIB2TRIB2tribbles homolog 2 (Drosophila)
CSNK1DCSNK1Dcasein kinase 1, delta
CSNK1ECSNK1Ecasein kinase 1, epsilon
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1

Troyanskaya Laboratory - Princeton University