ASD

GO:0071636 positive regulation of transforming growth factor-beta production (9)

GeneInput weightStandardRank
CREB1--100
SMAD3--823
ATF2--1309
PTGS20.2515085
XCL1--7819
WNT11--7820
FOXP3--112457
THBS1--24444
ATP6AP2--25361

Network

GO:0071636

Network
Enrichment
NameDescriptionExternal IDs
CREB1cAMP responsive element binding protein 1 Entrez:1385  HGNC: 2345  HPRD: 00442  Ensembl: ENSG00000118260 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
ATF2activating transcription factor 2 Entrez:1386  Ensembl: ENSG00000115966  HPRD: 00443  HGNC: 784 
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) Entrez:5743  Ensembl: ENSG00000073756  HGNC: 9605  HPRD: 02599 
XCL1chemokine (C motif) ligand 1 Entrez:6375  HGNC: 10645  HPRD: 02595  Ensembl: ENSG00000143184 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CREB1cAMP responsive element binding protein 1
SMAD3SMAD family member 3
ATF2activating transcription factor 2
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
XCL1chemokine (C motif) ligand 1
Query geneGeneGene descriptionEdge score
CREB1CREB1cAMP responsive element binding protein 1
SMAD3SMAD3SMAD family member 3
ATF2ATF2activating transcription factor 2
PTGS2PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
XCL1XCL1chemokine (C motif) ligand 1

Troyanskaya Laboratory - Princeton University