ASD

GO:0052200 response to host defenses (9)

GeneInput weightStandardRank
SMAD3--823
GUCY1A3--1997
SLC25A6--2820
TLR4--112795
TLR7--13389
TGFB10.25120135
EIF2AK2--21530
TLR1--21623
TLR3--22478

Network

GO:0052200

Network
Enrichment
NameDescriptionExternal IDs
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
GUCY1A3guanylate cyclase 1, soluble, alpha 3 Entrez:2982  HGNC: 4685  HPRD: 00768  Ensembl: ENSG00000164116 
SLC25A6solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 Entrez:293  HPRD: 02461  HGNC: 10992 
TLR4toll-like receptor 4 Entrez:7099  Ensembl: ENSG00000136869  HGNC: 11850  HPRD: 04325 
TLR7toll-like receptor 7 Entrez:51284  Ensembl: ENSG00000196664  HGNC: 15631  HPRD: 02295 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SMAD3SMAD family member 3
GUCY1A3guanylate cyclase 1, soluble, alpha 3
SLC25A6solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
TLR4toll-like receptor 4
TLR7toll-like receptor 7
Query geneGeneGene descriptionEdge score
SMAD3SMAD3SMAD family member 3
GUCY1A3GUCY1A3guanylate cyclase 1, soluble, alpha 3
SLC25A6SLC25A6solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
TLR4TLR4toll-like receptor 4
TLR7TLR7toll-like receptor 7

Troyanskaya Laboratory - Princeton University