ASD

GO:0006704 glucocorticoid biosynthetic process (10)

GeneInput weightStandardRank
CRH--563
CACNA1H1.013855
CYP17A10.2513984
HSD3B2--4818
HSD3B1--5560
CYP11B10.2516613
HSD11B10.2518910
HSD11B2--9892
CYP21A20.25113362
CYP11B2--13660

Network

GO:0006704

Network
Enrichment
NameDescriptionExternal IDs
CRHcorticotropin releasing hormone Entrez:1392  Ensembl: ENSG00000147571  HPRD: 07172  HGNC: 2355 
CACNA1Hcalcium channel, voltage-dependent, T type, alpha 1H subunit Entrez:8912  HPRD: 07442  HGNC: 1395  Ensembl: ENSG00000196557 
CYP17A1cytochrome P450, family 17, subfamily A, polypeptide 1 Entrez:1586  HPRD: 01944  Ensembl: ENSG00000148795  HGNC: 2593 
HSD3B2hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Entrez:3284  HPRD: 01941  HGNC: 5218  Ensembl: ENSG00000203859 
HSD3B1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Entrez:3283  HGNC: 5217  HPRD: 04920  Ensembl: ENSG00000203857 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CRHcorticotropin releasing hormone
CACNA1Hcalcium channel, voltage-dependent, T type, alpha 1H subunit
CYP17A1cytochrome P450, family 17, subfamily A, polypeptide 1
HSD3B2hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSD3B1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Query geneGeneGene descriptionEdge score
CRHCRHcorticotropin releasing hormone
CACNA1HCACNA1Hcalcium channel, voltage-dependent, T type, alpha 1H subunit
CYP17A1CYP17A1cytochrome P450, family 17, subfamily A, polypeptide 1
HSD3B2HSD3B2hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSD3B1HSD3B1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

Troyanskaya Laboratory - Princeton University