ASD

GO:0030900 forebrain development (225)

GeneInput weightStandardRank
GNAO1--4
ATRX--136
PLCB1--148
SLIT1--61
GRIN2A0.25166
PAFAH1B10.25174
ERBB40.25186
CREB1--100
CNTNAP21.01115
SLC1A2--119
NFIB--120
NEUROD1--1127
GNAQ--189
SOX2--1200
FGFR2--1237
SSTR2--251
LRP6--279
GRIN1--294
RARB0.251300
SLC8A2--334
MYH10--366
NF10.251372
ASCL1--413
GSK3B--427
SALL1--506
PAX60.251544
NEUROD6--556
VLDLR0.251574
CDK5R1--586
NPY0.251592
TOP2B--615
RELN1.01626
LHX2--655
SLIT2--659
FOXG1--661
CNTN2--674
FABP70.251678
PGAP1--711
POU3F2--750
DICER1--1762
GRIN2B1.01763
TSC10.251790
SMARCA4--801
HPRT1--1842
PCSK1--898
DRD10.251899
FYN--932
CHRD--941
NR4A3--1963
NR2E10.251977
LRP20.251984
NR4A20.251992
YWHAE--995
ID4--1009
NCOR1--1019
NDEL10.2511074
BCL11B--1125
BMPR1A--1140
RFX4--1148
ROBO2--11202
DLC1--1282
FEZF20.2511366
HDAC2--1440
SALL3--1487
LEF1--1499
APP--1515
SLC8A1--1529
PRKG1--1553
RAC1--1617
WNT2B--1673
NR2F1--1728
AKAP5--1759
BCAN--1869
ZEB1--11901
OTX2--11916
ISL1--1974
TYRO3--2083
ID2--2154
ROBO1--2182
FGFR1--2262
MAPK8IP3--2274
NR0B1--12278
SOX3--2303
DLX20.2512357
DLX10.2512400
ATP7A--12483
SIX3--12494
EGFR--12546
LHX1--2560
HTR5A0.2512606
EMX1--2613
FGFR3--12640
DPYSL2--2672
LRP8--2732
RTN4--2735
SRC--2825
PTPRS--2838
NOTCH1--12865
SKI--2904
NR2F2--2941
NEUROG2--2989
HOOK3--3126
MSX1--13127
GSX1--3159
CDK50.2513194
LHX6--3241
GATA2--13291
WNT5A--3319
WNT8B--3407
CDON--3487
NUMBL--3618
OGDH--3680
DIXDC1--3734
DRD20.2513749
ALDH1A2--3771
AVPR1A0.513803
CYP19A10.2513823
TNR--3868
LHX8--3904
CYP17A10.2513984
LHX5--3998
SLC8A3--4131
SLC6A40.2514137
NKX2-1--4142
FOXP20.514163
LMX1A--4236
GHRHR--4237
MAS1--4244
WNT1--4383
AGTPBP1--4391
AXIN1--14419
RAX--14486
FGF10--14532
OTX1--4602
DRAXIN--4717
WNT3A--4747
EXT10.2514780
BMP2--14855
HES5--4919
TH0.2514933
SRD5A10.2514966
MECOM--4979
NDST1--5114
FOXB1--5360
RYK--5383
PLXNA4--5391
NOG--15439
OTP--5490
HES10.2515912
ETS1--5943
GLI3--16261
ZEB2--6361
OXTR0.516388
UQCRQ--6404
BMP4--16499
PCM1--16569
GDF7--6682
AVPR2--17031
WNT7B--7113
CX3CR1--7136
PEX5--17148
FRS2--7173
PRTFDC1--7244
GLI2--17307
WNT7A--7312
GHRH--7478
SLC6A30.517659
CXCL12--7802
NUMB--7848
CYP11A10.2518063
KDM2B--8359
GSX2--8581
TAL2--8785
LRRK2--18802
CTNNB10.519066
RAB3GAP1--9492
GSC--9702
HSD17B30.2519988
BBS4--110131
GNG12--10259
SMO0.25110504
ATOH1--11336
AHSG--11515
DKK1--11567
CEP120--11598
DUOX2--111733
CCKAR--11747
NKX2-6--111887
KDM1A--12183
IFT88--12504
EOMES--12952
FGF2--13150
MKKS--114510
FEZF10.25116009
EFNA2--16629
TBX19--17620
SSTR3--18309
PSEN1--18523
SHH--118571
TP73--18810
CHRNB20.25120216
HESX1--20692
KAT2A--21262
RPGRIP1L--21472
PITX10.25121646
TACC3--21671
ALDH1A3--21739
WNT4--21809
ARX0.25121856
BBS2--121914
NOTCH3--22114
AQP1--22433
MDK--22733
UCHL5--22745
ANXA3--22980
E2F1--23057
PSEN2--23095
CDH1--123589
WDR62--23710
ATG7--23978
PEX13--124461
AXL--24522
HTRA2--124821
TWSG1--24840
ASPM--124942

Network

GO:0030900

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
ATRXalpha thalassemia/mental retardation syndrome X-linked Entrez:546  HGNC: 886  HPRD: 02069  Ensembl: ENSG00000085224 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
SLIT1slit homolog 1 (Drosophila) Entrez:6585  Ensembl: ENSG00000187122  HGNC: 11085  HPRD: 04773 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
ATRXalpha thalassemia/mental retardation syndrome X-linked
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
SLIT1slit homolog 1 (Drosophila)
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
ATRXATRXalpha thalassemia/mental retardation syndrome X-linked
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
SLIT1SLIT1slit homolog 1 (Drosophila)
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A

Troyanskaya Laboratory - Princeton University