ASD

GO:0014910 regulation of smooth muscle cell migration (22)

GeneInput weightStandardRank
SLIT2--659
RAPGEF40.251904
RPS6KB1--1521
IGF10.2512793
IGFBP5--3306
TRIB1--3431
IL6ST--3678
PDGFA--3731
LPAR1--4170
ADIPOQ0.2516032
ILK--7305
ACE--10304
F3--10889
VTN--13271
PLAU--20969
PDGFB--21071
LRP1--22276
IGFBP3--22342
CCL5--23042
PDGFRB--23242
P2RY2--24088
SERPINE10.25125055

Network

GO:0014910

Network
Enrichment
NameDescriptionExternal IDs
SLIT2slit homolog 2 (Drosophila) Entrez:9353  Ensembl: ENSG00000145147  HPRD: 04776  HGNC: 11086 
RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4 Entrez:11069  Ensembl: ENSG00000091428  HGNC: 16626  HPRD: 06929 
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1 Entrez:6198  Ensembl: ENSG00000108443  HGNC: 10436  HPRD: 10202 
IGF1insulin-like growth factor 1 (somatomedin C) Entrez:3479  HPRD: 00936  Ensembl: ENSG00000017427  HGNC: 5464 
IGFBP5insulin-like growth factor binding protein 5 Entrez:3488  HGNC: 5474  Ensembl: ENSG00000115461  HPRD: 00901 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SLIT2slit homolog 2 (Drosophila)
RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1
IGF1insulin-like growth factor 1 (somatomedin C)
IGFBP5insulin-like growth factor binding protein 5
Query geneGeneGene descriptionEdge score
SLIT2SLIT2slit homolog 2 (Drosophila)
RAPGEF4RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4
RPS6KB1RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1
IGF1IGF1insulin-like growth factor 1 (somatomedin C)
IGFBP5IGFBP5insulin-like growth factor binding protein 5

Troyanskaya Laboratory - Princeton University