ASD

GO:0032008 positive regulation of TOR signaling cascade (12)

GeneInput weightStandardRank
RICTOR--537
RHEB--3728
RRAGA--4695
MLST8--5028
RRAGB--6607
RRAGC--7372
GOLPH3--8151
LAMTOR2--8770
RRAGD--9082
RPTOR--14284
LAMTOR3--20937
LAMTOR1--22090

Network

GO:0032008

Network
Enrichment
NameDescriptionExternal IDs
RICTORRPTOR independent companion of MTOR, complex 2 Entrez:253260  HGNC: 28611  HPRD: 10682  Ensembl: ENSG00000164327 
RHEBRas homolog enriched in brain Entrez:6009  HGNC: 10011  HPRD: 03188  Ensembl: ENSG00000106615 
RRAGARas-related GTP binding A Entrez:10670  HPRD: 10205  HGNC: 16963  Ensembl: ENSG00000155876 
MLST8MTOR associated protein, LST8 homolog (S. cerevisiae) Entrez:64223  Ensembl: ENSG00000167965  HGNC: 24825  HPRD: 17031 
RRAGBRas-related GTP binding B Entrez:10325  HGNC: 19901  HPRD: 06710  Ensembl: ENSG00000083750 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RICTORRPTOR independent companion of MTOR, complex 2
RHEBRas homolog enriched in brain
RRAGARas-related GTP binding A
MLST8MTOR associated protein, LST8 homolog (S. cerevisiae)
RRAGBRas-related GTP binding B
Query geneGeneGene descriptionEdge score
RICTORRICTORRPTOR independent companion of MTOR, complex 2
RHEBRHEBRas homolog enriched in brain
RRAGARRAGARas-related GTP binding A
MLST8MLST8MTOR associated protein, LST8 homolog (S. cerevisiae)
RRAGBRRAGBRas-related GTP binding B

Troyanskaya Laboratory - Princeton University