ASD

GO:0030514 negative regulation of BMP signaling pathway (26)

GeneInput weightStandardRank
TRIM33--1147
SFRP1--387
CHRD--941
HIPK2--1051
SMAD7--1192
LEMD3--12084
SMAD6--2305
NOTCH1--12865
SKI--2904
SOSTDC1--3003
SMURF1--3060
WNT5A--3319
BMPER--3497
GREM1--3867
SFRP2--5252
NOG--15439
SOST--6885
CER1--6956
VWC2--8879
FBN1--110976
DKK1--11567
SKOR1--12870
FZD1--20775
TWSG1--24840
FSTL3--25154
CAV1--125381

Network

GO:0030514

Network
Enrichment
NameDescriptionExternal IDs
TRIM33tripartite motif containing 33 Entrez:51592  HPRD: 10423  HGNC: 16290  Ensembl: ENSG00000197323 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
CHRDchordin Entrez:8646  Ensembl: ENSG00000090539  HGNC: 1949  HPRD: 04592 
HIPK2homeodomain interacting protein kinase 2 Entrez:28996  HPRD: 06039  HGNC: 14402  Ensembl: ENSG00000064393 
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TRIM33tripartite motif containing 33
SFRP1secreted frizzled-related protein 1
CHRDchordin
HIPK2homeodomain interacting protein kinase 2
SMAD7SMAD family member 7
Query geneGeneGene descriptionEdge score
TRIM33TRIM33tripartite motif containing 33
SFRP1SFRP1secreted frizzled-related protein 1
CHRDCHRDchordin
HIPK2HIPK2homeodomain interacting protein kinase 2
SMAD7SMAD7SMAD family member 7

Troyanskaya Laboratory - Princeton University